2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione CAS: 446292-07 -5
Inombolo Yekhathalogu | XD93407 |
Igama lemveliso | 2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione |
CAS | 446292-07-5 |
Ifomu yemolekyulila | I-C21H21N3O5 |
Ubunzima beMolekyuli | 395.41 |
Iinkcukacha zokuGcina | I-Ambient |
Ukucaciswa kweMveliso
Imbonakalo | Umgubo omhlophe |
uAsay | 99% imizuzu |
Ikhompawundi 2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione yinkimbinkimbi i-molecule ye-organic enezicelo ezinokubakho kwintsimi yamachiza kunye ne-chemistry yamayeza.Ubukho be-isoindole core bubonisa ukuba le khompawundi ineempawu ezithile zesakhiwo ezihambelana ne-biologically kwaye zifunyenwe kwiimolekyuli ze-bioactive.I-Isoindole derivatives ziye zaxelwa ukuba zibonise uluhlu olubanzi lwemisebenzi ye-pharmacological, kubandakanywa ukulwa nokudumba, i-antitumor, kunye ne-antimicrobial properties.I-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl iqela kule khompawundi iqulathe hydroxyl iqela (OH) encanyathiselwe kwitsheyini ezintathu-carbon, nto leyo eyenza umqolo le moiety.Ikwanayo neqela le-phenyl elifakwe endaweni ye-morpholinone moiety.I-Morpholines isetyenziswe ngokubanzi kwi-chemistry yamachiza ngenxa yokukwazi ukusebenzisana neenjongo ezahlukeneyo zezinto eziphilayo kwaye ifakwe kumachiza amaninzi anemisebenzi eyahlukeneyo. banakho ukusebenza njenge-ligand okanye imodyuli kwiithagethi ezithile zeemolekyuli ngaphakathi komzimba.Iikhompawundi ezisekelwe kwi-carbonyl zisetyenziswe ekufumaneni iziyobisi ukusebenzisana ne-enzymes, i-receptors, okanye iiprotheni ezibandakanyekayo kwiinkqubo zesifo ezahlukahlukeneyo.Nangona kunjalo, ngaphandle kolwazi oluthe ngqo malunga nomsebenzi webhayoloji yale khompawundi okanye iithagethi ezithile, kulucelomngeni ukunika inkcazo ebanzi malunga nenkqubo yesifo. ukusetyenziswa okunokwenzeka.Uphando olongezelelweyo kunye novavanyo luya kufuneka ukufumanisa iimpawu zayo zekhemesti ezichanekileyo.Ekuqukumbeleni, ikhompawundi 2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl ]-1H-isoindole-1,3 (2H) -dione, kunye ne-isoindole core kunye namaqela asebenzayo, inezicelo ezinokuthi zenze kwintsimi yamachiza kunye nekhemistri yonyango.Ukusetyenziswa kwayo okuthe ngqo kunye nendlela yokwenza kuya kufuneka iphononongwe ngakumbi ngophando kunye nokulinga.