Iimveliso

I-2-[(6-Chloro-3,4-dihydro-3-Methyl-2,4-dioxo-1 (2H)-pyrimidinyl)Methyl]benzonitrile, edla ngokubizwa ngokuba yigama elithile elihlanganisiweyo okanye isakhiwo sekhemikhali, i-compound enezicelo ezininzi kwiinkalo ezahlukeneyo, kubandakanywa amayeza, i-agrochemicals, kunye ne-chemistry yezixhobo.Kwishishini lamachiza, le khompawundi ibonisa amandla njenge-scaffold okanye isakhiwo esisisiseko sokuphuhliswa kwamachiza anoveli.Ubume bayo beekhemikhali ezizodwa bubonelela ngamathuba ohlengahlengiso ngakumbi kunye nokwenza ngcono ukunyusa imisebenzi efunwayo ye-pharmacological okanye kujoliswe kwiindlela ezithile zesifo.Iikhemisti zamayeza kunye nabaphandi banokusebenzisa le khompawundi njengesiqalo sokuyila kunye nokwenza iimolekyuli ezintsha ezinokusetyenziselwa unyango.Ngokuzisa i-substituents ezifanelekileyo kwi-core structure, zinokwenza izinto eziphuma kuzo ezinokuthi ziphucule amandla, ukukhetha, kunye neempawu ze-pharmacokinetic.Ngaphezu koko, le ngqungquthela inokusebenza njengesakhiwo esibalulekileyo ekuhlanganiseni iamolekyu eziyinkimbinkimbi okanye abaviwa beziyobisi.Amaqela alo asebenzayo avumela ukuguqulwa kweekhemikhali ngakumbi, okwenza ukuba kuqhotyoshelwe amatyathanga ahlukeneyo asecaleni, i-moieties esebenzayo, okanye amaqela e-bioactive.Oku kuguquguquka kuququzelela ukudalwa kwezinto ezihlukeneyo ezinokuthi zihlolwe kwiintlobo ezininzi zezicelo, ezifana ne-antibacterial, antiviral, okanye i-anticancer agents.Kwintsimi ye-agrochemicals okanye ukukhuselwa kwezityalo, le ngqungquthela inokuthi ibonise iimpawu ze-pesticide.Ngohlengahlengiso olufanelekileyo kunye nokwenza ngcono, inokusebenza njengesandulela sokudityaniswa kwemichiza yokutshabalalisa ukhula, imichiza yokungunda, okanye imichiza yokutshabalalisa izinambuzane.Izazinzulu zezoLimo kunye nabaphandi banokuhlola amandla ayo okuphuhlisa iikhompawundi ezintsha ezilwa ngokufanelekileyo nezinambuzane, ukhula, okanye izifo zezityalo ngelixa zinciphisa impembelelo yokusingqongileyo.Ngaphezu koko, le ngqungquthela inokufumana izicelo kwi-chemistry yezinto, ngokukodwa ekuphuhliseni izinto ezisebenzayo okanye iipolymers.Ubume bayo obukhethekileyo bunokusetyenziswa njenge-monomer okanye ibhloko yokwakha ukudibanisa iipolymers ezineempawu ezithile.Ngokudibanisa kwi-polymer backbone, izazinzulu ziyakwazi ukulungelelanisa iipropati ezifana ne-solubility, ukuzinza kwe-thermal, ukuhanjiswa kombane, okanye iimpawu ze-optical.Ezi polymers emva koko zinokuqeshwa kwizicelo ezahlukeneyo, ukusukela kwi-elektroniki kunye ne-sensor ukuya kwi-biomaterials kunye neenkqubo zokuhanjiswa kweziyobisi. Kubalulekile ukuqaphela ukuba uphando oluneenkcukacha, uvavanyo olucokisekileyo, kunye novavanyo olungqongqo lokhuseleko kufuneka lwenziwe kuyo nayiphi na ikhompawundi ethile phambi kokusetyenziswa kwayo kwezorhwebo okanye isicelo.Ukuqonda ulwakhiwo-ubudlelwane bomsebenzi, iiprofayili zetyhefu, kunye neempembelelo ezinokuthi zibe kho kokusingqongileyo zibalulekile kusetyenziso olunoxanduva noluzinzileyo. Isishwankathelo, 2-[(6-Chloro-3,4-dihydro-3-Methyl-2,4-dioxo-1) (2H)-pyrimidinyl)I-Methyl]benzonitrile ibambe isithembiso njengekhompawundi eguquguqukayo kunye nezicelo kumachiza, kwi-agrochemicals, kunye ne-chemistry yezinto.Iimpawu zayo zesakhiwo zibonelela ngamathuba okufunyanwa kweziyobisi, ukuhlanganiswa kweekhompawundi zenoveli, uphuhliso lwezixhobo zokusebenza, kunye nokunye.Nangona kunjalo, uphando olongezelelweyo kunye nophuhliso luyafuneka ukuze kuphononongwe ngokupheleleyo kwaye kusetyenziswe amandla alo kwezi nkalo zahlukeneyo.