Iimveliso

I-2,2,2-Trifluoroethanol isiselo esinxilisayo esifumana izicelo ezininzi ezibalulekileyo kwiinkalo ezahlukeneyo, kubandakanywa amayeza, i-agrochemicals, kunye nesayensi yezinto.Iimpawu zayo ezikhethekileyo zeekhemikhali zenza ibhloko yokwakha exabisekileyo kunye ne-reagent kwi-synthesis.Onye ukusetyenziswa okukhulu kwe-2,2,2-trifluoroethanol njenge-solvent kunye ne-co-solvent.Iyakwazi ukunyibilikisa uluhlu olubanzi lweekhompawundi eziphilayo kunye ne-inorganic ngenxa ye-polarity eyomeleleyo kunye ne-hydrogen bond yokunikela amandla.Oku kuyenza ibe luncedo ngakumbi kwiinkqubo ezifuna ukusonjululwa komceli mngeni we-substrates, njenge-polar kunye ne-nonpolar solutes, iityuwa zetsimbi, okanye iipolymers.Ngokuqhelekileyo isetyenziswe kuphando lwamachiza kunye nophuhliso njenge-solvent ye-peptide synthesis kunye ne-co-solvent yokuphucula ukunyibilika kwamachiza angenakunyibilika kakubi.Iyakwazi ukungena endaweni ye-nucleophilic, i-acylation, kunye ne-condensation reactions ngenxa yobukho beqela elinamandla le-electron-withdrawing trifluoromethyl kunye neqela elisebenzayo le-hydroxy.Ezi mpendulo zinokubangelwa bubukho beziseko ezomeleleyo okanye iiasidi.Kubaluleke kakhulu kwiimpendulo ezifuna ukuqaliswa okanye ukuguqulwa kwe-trifluoromethyl substituents, njengoko isebenza njengomthombo weqela le-trifluoromethyl.Kwi-organic synthesis, i-2,2,2-trifluoroethanol isoloko isetyenziselwa ukuhlanganiswa kwee-fluorinated compounds.Inokuthi isebenze njenge-precursor ukudala i-trifluoromethylated okanye i-fluorinated block blocks, ebalulekileyo ekuphuhliseni amayeza kunye neekhemikhali ze-agrochemicals.Iqela le-trifluoromethyl linokuphucula i-bioactivity kunye nokuzinza kwe-metabolic yeemolekyuli zamachiza, okwenza kube ziithagethi ezikhangayo kwi-chemistry yamayeza.Ngaphezu koko, i-2,2,2-trifluoroethanol iqeshwe njenge-arhente yokuxazulula i-chiral ngenxa yokukwazi ukwenza i-hydrogen bonding complexes kunye ne-chiral. iikhompawundi.Le propati ivumela ukwahlula ii-enantiomers, eziyi-isomers zesibuko se-molecule, kwaye ibalulekile kwimveliso ye-optically pure ye-pharmaceutical ingredients.Ngelixa i-2,2,2-trifluoroethanol ibonelela ngeenzuzo ezininzi kwizicelo ezahlukeneyo, kubalulekile ukuphatha ngayo ngononophelo ngenxa yetyhefu kunye nendalo enokuba yingozi.Amanyathelo okhuseleko afanelekileyo, kubandakanywa nokusetyenziswa kwezixhobo zokukhusela zomntu kunye nokusebenza kwindawo enomoya, kufuneka ilandelwe ukuze kuqinisekiswe ukhuseleko lomsebenzisi kunye nokuthintela nayiphi na ingozi yengozi.Ngokufutshane, i-2,2,2-trifluoroethanol i-compound versatile. efumana ukusetyenziswa okuninzi kumashishini ahlukeneyo.Isakhono sayo sokusebenza njenge-solvent, i-reagent, kunye ne-arhente yokusombulula i-chiral iyenza ixabiseke kwizicelo ezahlukeneyo, kubandakanywa uphuhliso lwamachiza kunye nokudibanisa imathiriyeli.Nangona kunjalo, kufuneka kuqwalaselwe xa uyisebenzisa, ukunamathela kwiiprotokholi zokhuseleko ezichanekileyo zokuqinisekisa impilo-ntle yomsebenzisi kunye nempumelelo yeenkqubo zemichiza ezifunwayo.