Iimveliso

I-2,3-Difluoro-4-ethoxybenzeneboronic acid yi-chemical compound enezicelo ezibalulekileyo kwi-organic synthesis, ngokukodwa kwi-chemistry yamayeza kunye nophando lwamachiza.I-derivative ye-boronic acid ebonisa iringi ye-benzene endaweni ye-athom ezimbini ze-fluorine, iqela le-ethoxy (-OCH2CH3), kunye neqela le-boronic acid (-B (OH) 2) kwindawo ye-4.Enye yezinto eziphambili zokusetyenziswa kwe-2, I-3-Difluoro-4-ethoxybenzeneboronic acid ifana nebhloko yokwakha i-synthesis ye-biologically active compounds.Iqela le-boronic acid liyi-handle esebenzayo enokuthi ithathe inxaxheba kwiindlela ezahlukeneyo zeekhemikhali, ezifana ne-Suzuki-Miyaura-cross-coupling reactions, evumela ukuqaliswa kwamaqela ahlukeneyo asebenzayo.Le ngqungquthela inokufakwa kwi-synthesis ye-pharmaceutical agents ezijolise kwizifo ezithile kunye neenkqubo zezinto eziphilayo.Ubukho be-athomu ye-fluorine kunye neqela le-ethoxy linokuzisa ukuzinza okuphuculweyo kwe-metabolic, i-bioactivity, kunye neempawu ze-pharmacokinetic kumachiza avelayo.Ngaphezu koko, i-2,3-Difluoro-4-ethoxybenzeneboronic acid ingasetyenziswa ekuphuhliseni i-probes ye-fluorescent kunye ne-sensors.Iqela le-asidi ye-boronic linobudlelwane obukhethekileyo bee-diols, eziqhelekileyo zifumaneka kwii-biomolecules ezifana ne-saccharides kunye ne-nucleic acids.Le propati ivumela i-compound ukuba idibanise ngokukhethayo kwaye ibone iamolekyu ezijoliswe kuyo, ivumela ukuyilwa kwezixhobo ezibukhali kakhulu kunye nezixhobo ezithile zokuxilonga.Ukudityaniswa kweeathom zefluorine kwiringi ye-benzene kunokubonelela ngeempawu ezintle ze-spectroscopic, ezifana nokwanda kwe-fluorescence intensity okanye i-wavelength shifts, ephucula ukuchaneka nokuthembeka kweprobes.Olunye usetyenziso oluphawulekayo lwe-2,3-Difluoro-4-ethoxybenzeneboronic acid lies kwisicelo sayo esinokubakho njengebhloko yokwakha yokudibanisa izinto ezineempawu eziphambili.I-Boronic acid derivatives isoloko isetyenziswa ekudibaneni kweepolymers ezisebenzayo, ezinokuqeshwa kwiinkalo ezahlukeneyo, kubandakanywa inzululwazi yezinto, iinkqubo zokuhanjiswa kweziyobisi, kunye nezivamvo.Inhlanganisela ekhethekileyo yokusebenza kwe-boronic acid kunye nokutshintshwa kwe-fluorine kule khompawundi inikezela ngamathuba okulungelelanisa iipropati zezixhobo ezibangelwayo, ukuphucula iimpawu ezifana nokunyibilika, ukuzinza, kunye nokuhambelana kwiithagethi ezithile.Xa uphethe i-2,3-Difluoro-4-ethoxybenzeneboronic acid. , kubalulekile ukulandela imigaqo yokhuseleko efanelekileyo, kuquka ukunxiba izixhobo zokuzikhusela nokusebenza kwindawo engenamoya.I-Boronic acids inokukhathazeka emoyeni kunye nomswakama, ngoko kuyacetyiswa ukuba ugcinwe kwaye uziphathe phantsi kweemeko ezingenasiphelo ukuze zigcine ukusebenza kwazo kunye nokuzinza. ngakumbi kwikhemikhali yezamayeza, uphuhliso lweprobe ye-fluorescent, kunye nesayensi yezixhobo.Ukusebenza kwayo kwe-boronic acid, kunye ne-fluorine kunye namaqela e-ethoxy, igalelo ekusetyenzisweni kwayo kwizinto ezininzi kunye nokusetyenziswa okunokwenzeka ekuyileni i-biologically active compounds, izixhobo zokuxilonga, kunye nezixhobo eziphambili.Uphando oluqhubekayo kunye nokuphononongwa kokuphinda kusebenze kunye neepropathi zinokutyhila ukusetyenziswa okungaphezulu kwaye zibonelele ngemibono kwizicelo ezitsha kwiinkalo ezahlukeneyo zenzululwazi.