Iimveliso

I-2,3-Difluoro-4-ethoxybenzeneboronic acid yi-compound efumana usetyenziso kwiinkalo ezininzi ze-chemistry, ngokukodwa kwi-organic synthesis kunye ne-chemistry yamayeza.Ngesakhiwo sayo esiyingqayizivele kunye ne-reactivity, ibe yinto ebalulekileyo yokwakha i-molecule ye-organic complex kunye ne-pharmaceutical compounds.Enye yezicelo eziphambili ze-2,3-Difluoro-4-ethoxybenzeneboronic acid ilele ekusetyenzisweni kwayo kwi-cross-coupling reactions.Iimpendulo zokudibanisa, ezifana ne-Suzuki-Miyaura kunye ne-Buchwald-Hartwig couplings, iindlela ezinamandla zokwenza i-carbon-carbon kunye ne-carbon-heteroatom bond.Kule mpendulo, i-2,3-Difluoro-4-ethoxybenzeneboronic acid ingasebenza njenge-boronate ester component, iphendule ngee-electrophiles ezahlukeneyo (umzekelo, i-aryl halides, i-vinyl halides) phantsi kwefuthe le-catalysts efanelekileyo.Oku kuvumela ukuhlanganiswa kwee-compounds ezahlukahlukeneyo kunye neempawu ezisebenzayo ze-biologically, ezifana ne-pharmaceutical agents okanye i-agrochemicals.Ngaphezu koko, ubukho be-athomu ye-fluorine kwi-2,3-Difluoro-4-ethoxybenzeneboronic acid inokunika iipropati eziluncedo kwii-athomu ezibangelwayo.Ukutshintshwa kwe-fluorine kunokunyusa uzinzo, i-lipophilicity, kunye neprofayili ye-pharmacokinetic yeekhompawundi ze-organic, ibenze babe ngabaviwa bamachiza asebenzayo.Ngoko ke, ukusetyenziswa kweqhinga le-2,3-Difluoro-4-ethoxybenzeneboronic acid njenge-precursor kwi-synthesis ye-compounds efana neziyobisi kunokubonelela ngokufikelela kwiimolekyuli ze-fluorinated kunye nomsebenzi ophuculweyo we-biological kunye nezinto ezinqwenelekayo ze-physicochemical. ,3-Difluoro-4-ethoxybenzeneboronic acid ibonelela ngezinto ezininzi ezahlukeneyo kwizicelo zokwenziwa.Inokuthi ifakwe kwi-nucleophilic substitution reactions, evumela ukuqaliswa kwamaqela ahlukeneyo asebenzayo kwindawo ye-ethoxy.Oku kwenza ukuba i-derivatization yekhompawundi ilungelelanise iipropati zayo ngeenjongo ezithile okanye ukwazisa iingongoma ezongezelelweyo zokwahluka kwithala leencwadi lokudibanisa ukufunyanwa kweziyobisi. Isishwankathelo, i-2,3-Difluoro-4-ethoxybenzeneboronic acid isebenza njengento ebalulekileyo ephakathi kwi-organic synthesis kunye ne-organic synthesis. chemistry yonyango.Ukuthatha inxaxheba kwayo ekuphenduleni ukudibanisa, ukufakwa kwee-athomu ze-fluorine, kunye nokuphuma kwi-ethoxy isikhundla kwenza kube sisixhobo esixabisekileyo sokwakhiwa kweentlobo ezahlukeneyo ze-organic compounds kunye nezicelo ezinokuthi zenziwe ngamachiza.Ukusetyenziswa kwayo kuvumela ukuhlanganiswa kweeamolekyu eziyinkimbinkimbi kunye neelayibrari zokufumana iziyobisi kunye nokubonelela ngokufikelela kwiikhompawundi ezine-fluorinated kunye neepropati eziphuculweyo.