I-2,3,5-Triphenyl-2H-tetrazolium chloride Cas: 298-96-4 98% I-Off-white / yellow crystalline powder
| Inombolo Yekhathalogu | XD90154 |
| Igama lemveliso | I-2,3,5-Triphenyl-2H-tetrazolium chloride |
| CAS | 298-96-4 |
| Ifomula yeemolekyuli | C19H15N4·Cl |
| Ubunzima beMolekyuli | 334.80 |
| Iinkcukacha zokuGcina | 2 ukuya ku-8 °C |
| IKhowudi yoMrhumo eHarmonized | 29339980 |
Ukucaciswa kweMveliso
| Imbonakalo | I-off-white / yellow crystalline powder |
| uAsay | Min.98% |
| Indawo yokunyibilika | 235 - 245 Deg C |
| Ilahleko ekomisweni | <3.0% |
| Umxholo wamanzi | 0.5% Ubuninzi |
| Intsalela kwi-Ignition | Max.0.5% |
| Ukunyibilika kwi-EtoH | Dlula |
| Ukunyibilika kwi-Ethanol | Icace kwaye igqibe |
Ukuphanda umphumo onenzuzo wokudibanisa i-butyrate, i-Lactobacillus casei, kunye ne-L-carnitine kwimodeli ye-rat colitis.Iigundane zahlulwa zibe ngamaqela asixhenxe.Amaqela amane afumene i-butyrate yomlomo, i-L-carnitine, i-Lactobacillus casei kunye nokudibanisa ama-agent amathathu kwiintsuku ze-10 ezilandelelanayo.Amaqela aseleyo aquka ulawulo olubi kunye nolulungileyo kunye neqela le-sham.IMacroscopic, iimviwo ze-histopathological, kunye ne-biomarkers ezifana ne-tumor necrosis factor-alpha (TNF-α) kunye ne-interlukin-1β (IL-1β), i-myeloperoxidase (MPO), i-thiobarbituric acid reactive substances (TBARS), kunye ne-ferric yokunciphisa isakhono seplasma (FRAP) ) zigqitywe kwi-colon.Unyango oludibeneyo lubonise umphumo obalulekileyo wokunceda ekunciphiseni i-colitis xa kuthelekiswa nokulawula.Utshintsho ngokubanzi ekunciphiseni i-TNF-α (114.66 ± 18.26 vs 171.78 ± 9.48 pg / mg protein, P <0.05), IL-1β (24.9 ± 1.07 vs 33.06 ± 2.16 pg / mg protein, P2.), TBARS. ± 0.03 vs 0.49 ± 0.04 μg/mg iprotheni, P <0.01), i-MPO (15.32 ± 0.4 vs 27.24 ± 3.84 U / mg iprotheni, P <0.05), kunye nokuphakama kwe-FRAP (23.46 ± 1.3 ± 1.3/7 vs , P <0.05) ixhasa ukhetho lonyango oludibeneyo ngokuthelekiswa nokulawula.Nangona i-monotherapies nayo yayisebenza ekuphuculeni iimpawu ze-colitis, unyango oludibeneyo lwalungcono kakhulu ekuphuculeni iimpawu zoxinzelelo lwe-colon oxidative ezibandakanya i-FRAP, i-TBARS, kunye ne-MPO. imeko yeklinikhi.
