Iimveliso

I-compound 2,4,5-Trifluorobenzyl bromide yi-organic compound kunye ne-chemical formula C7H5BrF3.Yikhompawundi enevumba elimnandi eyeyeklasi yezinto eziphuma kwi-benzyl.I-compound ibonakaliswe kubukho be-athomu ezintathu ze-fluorine ezifakwe kwiqela le-benzyl kunye ne-athomu ye-bromine.Enye yezicelo eziphambili ze-2,4,5-trifluorobenzyl bromide i-organic synthesis.Ingasetyenziswa njengebhloko yokwakha eguquguqukayo ekulungiseleleni iikhompawundi ezahlukeneyo.Iqela le-trifluoromethyl kwikhompawundi linika i-reactivity eyodwa kunye neepropati ezinokusetyenziselwa ukuhlanganiswa kwee-molecule ze-organic complex.Ngokomzekelo, i-compound isetyenziswa ngokuqhelekileyo ekwakhiweni kwe-fluorinated pharmaceuticals, i-agrochemicals, kunye nezinye i-biologically active compounds.I-reactivity ye-2,4,5-trifluorobenzyl bromide inokubangelwa ubukho be-athomu ye-bromine.I-athomu ye-bromine isebenza njengeqela elishiyayo kwaye yenza ukuphendulwa kokutshintshwa apho i-bromine ithathelwa indawo ngamanye amaqela asebenzayo.Le propati yenza i-compound ibe luncedo kwi-synthesis ye-compounds ehlukeneyo ngokusebenza kweqela le-benzyl.Ukongezelela, i-athomu ye-fluorine ye-electron-withdrawing i-athom ye-fluorine inokuchaphazela ukuphinda kusebenze kunye nokuzinza kweemveliso ezivela kwi-2,4,5-trifluorobenzyl bromide.Ubukho be-athomu ye-fluorine inokunyusa ukuzinza kwe-metabolism yamachiza kunye nokwandisa i-lipophilicity, enokuchaphazela iimpawu zabo ze-pharmacokinetic, ezifana nokuxutywa kunye nokusabalalisa emzimbeni. kwiindlela ezahlukeneyo zeekhemikhali.Ngokomzekelo, inokuthatha inxaxheba kwiimpendulo zokudibanisa, ezifana ne-Suzuki-Miyaura cross-coupling, ukwenza iibhondi ze-carbon-carbon.Le mpendulo inezicelo ezibanzi kwi-pharmaceutical and agrochemical synthesis.Ekuqukumbeleni, i-2,4,5-Trifluorobenzyl bromide yi-compound eguquguqukayo kunye nezicelo kwi-organic synthesis.Iqela layo le-trifluoromethyl kunye ne-athomu ye-bromine inikezela ngamathuba okwakhiwa kwee-molecule eziyinkimbinkimbi kunye nokusebenza kweqela le-benzyl.Ukuphinda kusebenze kwekhompawundi kunye neempawu zenza ukuba zixabiseke xa kudityaniswa amayeza, imichiza yezolimo, kunye nezinye iikhompawundi ezisebenzayo ngokwebhayoloji.Ngaphaya koko, inokusebenza njenge-reagent eluncedo okanye ephakathi kwiindlela ezahlukeneyo zemichiza.