(2S,3R,4S,5S,6R)-2-(3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxymethyl)-2-methoxy -2H-pyran-3,4,5-triol CAS: 1279691-36-9
| Inombolo Yekhathalogu | XD93372 |
| Igama lemveliso | (2S,3R,4S,5S,6R)-2-(3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxymethyl)-2-methoxy -2H-pyran-3,4,5-triol |
| CAS | 1279691-36-9 |
| Ifomu yemolekyulila | C24H29ClO8 |
| Ubunzima beMolekyuli | 480.94 |
| Iinkcukacha zokuGcina | I-Ambient |
Ukucaciswa kweMveliso
| Imbonakalo | Umgubo omhlophe |
| uAsay | 99% imizuzu |
Ikhompawundi (2S,3R,4S,5S,6R)-2-(3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxymethyl)-2 I-methoxy-2H-pyran-3,4,5-triol yi-molecule eyinkimbinkimbi ye-organic kunye nezicelo ezinokuthi zibekho kwiinkalo ezahlukeneyo, kubandakanywa nekhemistri yamachiza kunye neyeza.Ikhompawundi iyingxenye yeklasi ye-pyranopyrans, eyi-cyclic compounds equkethe i-pyran ring edibeneyo. nenye iringi yephiran.Ubukho be-stereocenters ezininzi kwisakhiwo sayo kwenza i-molecule ye-chiral, oku kuthetha ukuba ikhona kwiifom ezimbini ze-enantiomeric ezinokuthi zibe nemisebenzi eyahlukeneyo yezinto eziphilayo.Iimpawu zesakhiwo se-molecule, ezifana ne-benzyl kunye ne-chlorophenyl amaqela, adityaniswe nobukho bamaqela amaninzi e-hydroxyl, acebisa ukuba inokubonisa umsebenzi webhayoloji.Iikhemisti zamachiza zinokuhlola amandla ekhompawundi njengekhompawundi ekhokelayo ekuphuhliseni amachiza amatsha, ngakumbi ezo zijolise kwizifo ezibandakanya i-carbohydrate metabolism.Ubukho beqela (S) -tetrahydrofuran-3-yloxy licebisa ukuba ikhompawundi inokuba namandla okusebenzisana. kunye ne-receptors okanye i-enzymes ezibandakanyekayo kwi-carbohydrate metabolism okanye iindlela zokubonisa.Abaphandi banokuphanda amandla ayo njenge-inhibitor okanye imodyuli yee-enzymes ezithile okanye ii-receptors ezibandakanyekayo kwezi nkqubo.Ukongezelela, i-compound ye-structural complexity ingenza ukuba ibe ngumviwa ofanelekileyo wokuphucula i-chemistry chemistry ngokusebenzisa ukuguqulwa kwesakhiwo.Ngaphezu koko, i-scaffold ye-pyranopyran ye-compound iqulethe amaqela amaninzi e-hydroxyl, amaqela abalulekileyo asebenzayo kuyilo lwamachiza.Amaqela e-Hydroxyl angathatha inxaxheba kwintsebenziswano ye-hydrogen bonding, echaphazela ukunyibilika kwekhompawundi, ukuzinza, kunye neempawu ze-pharmacokinetic.Iikhemisti zamayeza zinokunyusa la maqela ukuze kunyuswe amandla ekhompawundi, ukukhetha, kunye nezinye iipropathi ze-pharmacological.I-compounds structural complexity iphinda ibonise ukusetyenziswa okunokwenzeka kwisayensi yezinto kunye ne-organic synthesis.Ulungelelwaniso lwayo olulodwa lwamaqela asebenzayo lunokusetyenziselwa ukuhlanganiswa kwenoveli yekhompawundi eziphilayo ezineempawu ezithile okanye imisebenzi ethile.Ukongezelela, i-compound inokusebenza njengendawo yokuqala yokuphuhliswa kwezinto ezintsha, ezifana neepolymers okanye izakhiwo ze-supramolecular, kunye nezicelo ezinokubakho kumashishini ahlukeneyo.Ekuqukumbeleni, i-compound (2S, 3R,4S,5S,6R) -2- (3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxymethyl)-2-methoxy-2H-pyran-3,4,5-triol inokwakheka Iimpawu ezenza ukuba zibe luncedo kwikhemistri yezamayeza kunye namayeza, isayensi yezixhobo, kunye ne-organic synthesis.Ubume bayo obuntsonkothileyo kunye noluhlu olwahlukeneyo lwamaqela asebenzayo lubonelela ngamathuba ophononongo ekufumaneni iziyobisi, ukumodareyithwa kwe-enzyme, uphuhliso lwezixhobo, kunye nezinye iindawo zophando.
