Iimveliso

I-3-(3-iodopropyl) -7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-enye i-compound organic compound kunye nezicelo ezinokubakho kwi-chemistry yamayeza kunye nokufunyanwa kweziyobisi.Le khompawundi inolwakhiwo lweekhemikhali olulodwa oluyenza ixabiseke kuphuhliso lwamayeza amatsha ajolise kwiinkqubo ezithile zebhayoloji.Onye yezinto ezinokuthi zisetyenziswe le khompawundi kukukwazi ukusebenzisana neethagethi ezahlukeneyo zebhayoloji.Ubukho be-benzazepinone scaffold kwisakhiwo sayo buyenza ifane ne-neurotransmitters ethile kunye ne-receptors.Oku kufana kuvula amathuba okuba i-compound isetyenziswe njengendawo yokuqala yokwenziwa kweziyobisi ezijoliswe kwii-receptors ezithile kwinkqubo ye-nervous central.Ngokuguqula isakhiwo sale khompawundi, abaphandi banokwenza izinto eziphuma kuzo ezibonisa ukubophelela okukhethiweyo kwi-receptors ethile, enokubangela ukuba kufumaneke unyango olunoveli lwezifo ezifana nesifo sika-Parkinson, i-schizophrenia, kunye nezinye izifo ze-neurological.Ngaphezu koko, i-3-(3-iodopropyl) ) -7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-enye kunye nezinto eziphuma kuyo ziye zabonisa amandla njengama-anticancer agents.Iimpawu zeekhemikhali ezizodwa zekhompawundi ziyenza ikwazi ukusebenzisana neeseli zomhlaza, iphazamisa ukukhula kwazo kunye neendlela zokwanda kwazo.Izifundo zokuqala ziye zabonisa ukusebenza kwayo kwiindidi ezahlukeneyo zeeseli zomhlaza, okwenza kube ngumviwa othembisayo wophando olongezelelweyo kunye nophuhliso njengeyeza le-anticancer.Ngaphezu kwamandla ayo kwi-chemistry yamachiza, le ngqungquthela ingasetyenziselwa njengesixhobo sophando kwizifundo ze-neuroscience.Ukufana kwayo kwesakhiwo kwii-neurotransmitters ezithile kuvumela ukuba ulungelelanise umsebenzi we-neuronal kunye nomsebenzi we-receptor.Le propati iyenza ibe sisixhobo esixabisekileyo sokufunda iindlela zezifo ze-neurodeergenerative kunye nokuphazamiseka kwengqondo.Ngokuphonononga iimpembelelo ze-compound kwiindlela ze-neural kunye nokubonakaliswa, abaphandi banokufumana ingqiqo kwiindlela ezisisiseko zezi zifo kunye nokuchonga iindlela ezintsha zonyango. -2H-3-benzazepin-2-enye ibambe isithembiso esikhulu kwiinkalo zekhemikhali yamayeza kunye ne-neuroscience.Ubume bayo obukhethekileyo beekhemikhali buvumela ukuhlanganiswa kwezinto eziphumayo kunye neempawu zokubopha i-receptor ekujoliswe kuyo, okwenza kube sisixhobo esibalulekileyo sokufumana iziyobisi.Ngaphaya koko, amandla ayo njengearhente yokulwa nomhlaza kunye nokusetyenziswa kwayo kuphando lwe-neuroscience iqaqambisa ukuguquguquka kwayo ekunikeleni kwinkqubela phambili yesayensi kunye nophuhliso lonyango olutsha.Uphando oluqhubekayo kunye nokuphononongwa kwale khompawundi kunokukhokelela kwimpumelelo enkulu kumayeza nakwi-neuroscience.