Iimveliso

I-3-tert-Butoxycarbonylphenylboronic acid, eyaziwa ngokuba yi-Boc-Ph-B (OH) ₂, i-organic compound ephuma kwiklasi ye-boronic acids.Iqukethe ikhonkco ye-phenyl endaweni yeqela le-tert-butoxycarbonyl (Boc) kunye ne-boronic acid (-B (OH) ₂) iqela.Le ngqungquthela inoluhlu olubanzi lwezicelo kwi-organic synthesis, ngokukodwa kwintsimi ye-chemistry yamayeza.Ukusetyenziswa okuphambili kwe-3-tert-Butoxycarbonylphenylboronic acid njengeqela elikhuselayo kwi-organic synthesis.Iqela le-Boc linokongezwa ngokukhethiweyo kwiqela elisebenzayo le-amine ukuze likhusele ekuphenduleni okungafunekiyo ngexesha lokudityaniswa kwama-athomu anzima.Iqela elikhuselayo le-Boc lizinzile phantsi kweemeko ezahlukeneyo zokusabela kwaye linokususwa ngokulula kamva kusetyenziswa iimeko ezinobumuncu obuncinci, okuvumela ukukhuselwa okukhethiweyo kweqela le-amine.Le propati yenza i-3-tert-Butoxycarbonylphenylboronic acid i-reagent exabisekileyo kwi-synthesis ye-peptides, i-pharmaceuticals, kunye nemveliso yendalo.Ngaphezu koko, i-3-tert-Butoxycarbonylphenylboronic acid isetyenziswa ngokuqhelekileyo kwiimpendulo zokudibanisa, ezifana ne-Suzuki-Miyaura coupling.Iqela le-boronic acid liyakwazi ukusabela kunye neentlobo ze-organometallic, ngokuqhelekileyo i-aryl okanye i-alkyl boronate, okubangelwa ukubunjwa kwebhondi ye-carbon-carbon.Le ndlela yokusabela isetyenziswa ngokubanzi ukwenza izakhiwo ezintsonkothileyo zemolekyuli kunye nokwazisa amaqela e-aryl okanye alkyl kwimolekyuli ekujoliswe kuyo.I-3-tert-Butoxycarbonylphenylboronic acid, kunye neqela layo elikhuselayo le-Boc, ivumela ukuphendulwa kokudibanisa okukhethiweyo kwiindawo ezithile kwi-molecule, ukuphucula ubuninzi bokwenziwa kunye nokusebenza kakuhle.Ngaphezu koko, i-3-tert-Butoxycarbonylphenylboronic acid iphandiwe ngenxa yezicelo zayo zonyango.I-Boronic acids, kuquka i-phenylboronic acid derivatives, ibonise imisebenzi eyahlukeneyo yezinto eziphilayo, ezifana ne-anticancer, i-antiviral, kunye ne-antifungal properties.Ukukwazi kwe-3-tert-Butoxycarbonylphenylboronic acid ukuthatha inxaxheba kwiimpendulo zokudibanisa okunqamlezayo kunokudityaniswa ukuyila kunye nokudibanisa iikhompawundi zenoveli kunye nemisebenzi yebhayoloji eyandisiweyo.Abaphandi baphonononge ukuhlanganiswa kwe-boronic acid derivatives ye-3-tert-Butoxycarbonylphenylboronic acid kwaye bavavanya amandla abo e-pharmacological.Kuko konke, i-3-tert-Butoxycarbonylphenylboronic acid iyikhompawundi eguquguqukayo kunye nezicelo kwi-organic synthesis, ngakumbi njengeqela elikhuselayo nakwi-cross-coup iimpendulo.Ubume bayo obukhethekileyo beekhemikhali kunye nokusebenza kwakhona kwenza ukuba i-reagent ixabiseke kwi-synthesis yama-molecule anzima, kuquka i-peptides kunye namayeza.Ukongezelela, izicelo ezinokubakho zonyango ze-3-tert-Butoxycarbonylphenylboronic acid kunye ne-derivatives zayo ziyenza ibe yinto enomdla yokuhlola ngakumbi kwi-chemistry yamayeza.