Iimveliso

I-compound 4-[4-[(5S)-5-(aminomethyl)-2-oxo-3-oxazolidinyl]phenyl] -3-morpholinone hydrochloride yindlela ethile ye-compound echazwe kwimpendulo yangaphambili, apho ikhoyo. uhlobo lwetyuwa ye-hydrochloride.Ifom yetyuwa ye-hydrochloride isetyenziswa ngokuqhelekileyo kwizicelo zamachiza ngenxa yokuzinza kwayo okuphuculweyo, ukunyibilika, kunye nokulula kokwenziwa kwayo.Ubukho beqela le-oxazolidinyl kunye ne-morpholinone licebisa ukusebenzisana okunokwenzeka kunye neethagethi ezithile ze-biological, okwenza kube yibhloko yokwakha exabisekileyo ekufumaneni iziyobisi kunye nophuhliso.Iqela le-oxazolidinyl linokufumaneka kwii-antibacterial agents ezahlukahlukeneyo kwaye liyaziwa ngomsebenzi walo ngokuchasene nebhaktheriya echasene neziyobisi.Le khompawundi inokunceda ukoyisa ukwanda kokumelana ne-antibiotics ngokujolisa kwizifo zebhaktheriya ekunzima ukuyiphatha.I-morpholinone moiety, kwelinye icala, isetyenziswe ngokubanzi kwi-chemistry yamayeza ngenxa yokukwazi ukusebenzisana neethagethi zezinto eziphilayo.Ubukho beqela le-aminomethyl kwi-morpholinone libonisa ukuba kunokwenzeka ukusebenzisana okongeziweyo kunye neenkcukacha ezithile ekubopheni kwithagethi.Ukuqwalasela isakhiwo se-compound, sinokuba nezicelo njenge-antibacterial okanye i-antimicrobial agent.Uphando oluthe kratya luyafuneka ukuze kuqinisekiswe indlela ethile yokwenza izinto kunye nezinto ekujoliswe kuzo.Ukongezelela, i-pharmacokinetic ye-compound kunye ne-toxicological properties kufuneka ihlolwe ukuze kuqinisekiswe ukusebenza kwayo kunye neeprofayili zokhuseleko.Iqulunqwe njengetyuwa ye-hydrochloride, i-solubility ye-compound iphuculwe, iyenze ilungele ukulawulwa komlomo.Ifom yetyuwa iphinda ivumele ukuqulunqwa ngokulula kwiifom zedosi njengeepilisi okanye iipilisi.Ngokufutshane, i-compound 4-[(5S) -5-(aminomethyl) -2-oxo-3-oxazolidinyl]phenyl] -3- i-morpholinone hydrochloride ibonisa amandla kwintsimi yeyeza, ngokukodwa njenge-antibacterial okanye i-antimicrobial agent.Iimpawu zayo zesakhiwo kunye nefom yetyuwa ye-hydrochloride yenza ukuba ibe ngumgqatswa onomdla wokuqhubela phambili uphando kunye nophuhliso.Nangona kunjalo, uphando olongezelelweyo luyimfuneko ukumisela ukusetyenziswa kwayo okuthe ngqo, iindlela zokusebenza, kunye nokhuseleko kunye neeprofayili ezisebenzayo ngaphambi kokuba zisetyenziswe njenge-arhente yonyango.