Iimveliso

I-4-Carboxyphenylboronic acid yi-organic compound eyeyentsapho ye-boronic acids.Isakhiwo sayo sekhemikhali siquka i-athomu ye-boron edityaniswe neqela le-carboxyphenyl.Le khompawundi ifumene izicelo ezininzi kwiinkalo ezahlukeneyo ezifana organic synthesis, izinto zenzululwazi, chemistry amayeza, kunye catalysis.Enye yezicelo ezibalulekileyo 4-Carboxyphenylboronic acid kwindawo organic synthesis.Isetyenziswa ngokuqhelekileyo njenge-reagent kwi-palladium-catalyzed cross-coupling reactions, ngokukodwa kwi-Suzuki-Miyaura kunye ne-Chan-Lam yokudibanisa ukuphendula.Ngokuthatha inxaxheba njengomthombo we-boron, unokwenza iibhondi ze-carbon-carbon kunye ne-organic substrates, ezifana ne-aryl okanye i-vinyl halides.Oku kuvumela iikhemisti ukuba zenze iimolekyuli eziyinkimbinkimbi zezinto eziphilayo kunye neekhompawundi ezisebenzayo ngokufanelekileyo.Ikhono lokwazisa iqela le-carboxyphenyl libonelela ngeendlela ezahlukeneyo ekuguquleni nasekulungelelaniseni iipropati ze-compounds ezibangelwayo.Kwikhemikhali yamayeza, i-4-Carboxyphenylboronic acid ifumana izicelo kwi-design kunye ne-synthesis yama-molecule asebenzayo.Ivumela ukuqaliswa kwe-boronic acid moiety, enika iimpawu ezizodwa kunye nokuphinda kusebenze kwiikhompawundi ezijoliswe kuyo.Ngokomzekelo, i-boronic acids inokusebenza njenge-protease inhibitors, kwaye ngokubandakanya iqela le-carboxyphenylboronic acid, abaphandi banokukwazi ukulungelelanisa umsebenzi we-enzyme okanye bayile i-enzyme-targeted inhibitors.Ngaphezu koko, ubukho beqela le-carboxylic acid lenza ukuba i-compound yenze i-hydrogen bonds kunye ne-biomolecules, iphucula ukuxhamla kwayo kwi-protein receptors, ngaloo ndlela ichaphazela umsebenzi wabo we-biological. iibhondi ezine-polyols okanye iikhompawundi ezine-hydroxyl.Le propati ivumela ukuba iqeshwe njengenxalenye ekudityanisweni kwezinto eziphambili ezifana ne-hydrogels, i-bioconjugates, okanye iipolymers eziphendulayo.Ngokudibanisa i-4-Carboxyphenylboronic acid kwezi zinto, iipropati zabo zinokulungelelaniswa, zivumela izicelo ezifana neenkqubo zokuhanjiswa kweziyobisi, i-sensor, kunye nezixhobo ezihlakaniphile.Ukongezelela, iqela le-carboxyphenylboronic acid kule khompawundi lenza ukuba lisebenze njenge-catalyst kwiimpendulo ezininzi. .Ingathatha inxaxheba kwi-acid-base catalysis, esterification, kunye neempendulo ze-amidation.Lo msebenzi we-catalytic ungafakwa kwi-syntheuticals yamachiza, iikhemikhali ezintle, kunye nezinye iimolekyuli eziphilayo.Ekuqukumbeleni, i-4-Carboxyphenylboronic acid iyikhompawundi eguquguqukayo efumana uncedo kwiinkalo ezahlukeneyo zesayensi.Ukusetyenziswa kwayo kususela kwi-organic synthesis kunye ne-chemistry yamayeza ukuya kwisayensi yezinto kunye ne-catalysis.Ikhono layo lokuthatha inxaxheba kwi-palladium-catalyzed cross-coupling reactions, amandla ayo njengebhloko yokwakha i-biologically active compounds, kunye nendima yayo njenge-catalyst iyenza ibe sisixhobo esibalulekileyo kubaphandi ekufuneni ukuqhubela phambili ulwazi kunye nokuphuhlisa izisombululo ezintsha.