I-4-Chlorophenylboronic acid CAS: 1679-18-1
Inombolo Yekhathalogu | XD93447 |
Igama lemveliso | I-4-Chlorophenylboronic acid |
CAS | 1679-18-1 |
Ifomu yemolekyulila | C6H6BClO2 |
Ubunzima beMolekyuli | 156.37 |
Iinkcukacha zokuGcina | I-Ambient |
Ukucaciswa kweMveliso
Imbonakalo | Umgubo omhlophe |
uAsay | 99% imizuzu |
I-4-Chlorophenylboronic acid yi-organic compound efumana ukusetyenziswa okubanzi kwiinkalo ezahlukeneyo, kuquka i-organic synthesis, i-chemistry yamayeza, kunye nesayensi yezinto.Iqukethe indandatho ye-phenyl efakwe endaweni yeqela le-chloro (-Cl) kunye neqela le-boronic acid (-B (OH) 2) .Enye yezinto eziphambili zokusetyenziswa kwe-4-Chlorophenylboronic acid yindima yayo njenge-reagent exabisekileyo kwi-palladium-catalyzed. ukuphendula kokudibanisa, okufana neSuzuki-Miyaura kunye neempendulo zeHeck.Ezi mpendulo zibandakanya ukubunjwa kwebhondi ye-carbon-carbon, apho i-4-Chlorophenylboronic acid isebenza njengomthombo we-boron onokudibanisa kunye ne-electrophiles eyahlukeneyo yezinto eziphilayo, ezifana ne-aryl okanye i-vinyl halides.Oku kuvumela ukuhlanganiswa kweentlobo ezahlukeneyo ze-organic compounds, kubandakanywa amayeza, i-agrochemicals, kunye nezinto eziphathekayo.Ukongezelela, i-4-Chlorophenylboronic acid inokuguqulwa ngakumbi ngamachiza ukuzisa amaqela asebenzayo awongezelelweyo.Umzekelo, inokungena kwi-amination reactions ukwenza i-4-chloro-phenylboronates, enokuba luncedo phakathi kokudityaniswa kweekhompawundi ezahlukeneyo ezinenitrogen.Le ntlukwano yeqela elisebenzayo iphucula i-synthetic utility ye-4-Chlorophenylboronic acid, evumela ukudala iamolekyu eziyinkimbinkimbi kunye neempawu ezihambelanayo.Esinye isicelo esibalulekileyo se-4-Chlorophenylboronic acid sihlala kwi-chemistry yamayeza.Ibonise isithembiso njenge-pharmacophore okanye ibhloko yokwakha yokuphuhlisa i-bioactive compounds.Ngenxa ye-boronate moiety, i-4-Chlorophenylboronic acid inokwenza i-covalent bonds eguqukayo kunye ne-diol-containing molecules, ezifana ne-carbohydrates kunye ne-nucleotides.Oku kusebenzisana kuye kwaxhaswa ukuyila i-enzyme inhibitors, i-receptor ligands, kunye nezinye ii-agent zamachiza.Ngokomzekelo, i-boronic acid-based based proteasome inhibitors iye yaphuhliswa kunyango lwe-myeloma eninzi.Kwintsimi yezinto zesayensi, i-4-Chlorophenylboronic acid ifumene isicelo ekuguqulweni kweendawo okanye ukuhlanganiswa kwezinto ezisebenzayo.Ngokusebenzisa iqela le-boronic acid, linokwenza ii-complexes ezinamandla eziguqulwayo kunye ne-polyols okanye i-hydroxyl-containing compounds.Le propati ingasetyenziselwa ukusebenza komphezulu, njengokudalwa kweengubo eziphendulela i-stimuli okanye ukulungiswa kweenzwa zokubona i-carbohydrates okanye ezinye ii-analytes.Ngokufutshane, i-4-Chlorophenylboronic acid i-compound eguquguqukayo kunye nezicelo ezahlukeneyo kwi-organic synthesis, i-chemistry yamayeza. , kunye nesayensi yezinto.I-reactivity yayo kwi-carbon-carbon bond bond, ukukwazi ukuqaliswa kweqela elisebenzayo, kunye nokukwazi ukwenza i-covalent bonds ezibuyiselwayo kwenza kube sisixhobo esibalulekileyo kubaphandi kwiinkalo ezahlukeneyo zesayensi.