Kuphando oluqhubekayo lwechiza le-antidiabetic elikhuselekileyo nelisebenzayo, i-algae yaselwandle iba ngumthombo obalulekileyo obonelela ngeekhompawundi ezininzi zamandla amakhulu onyango.I-Alpha-amylase, i-alpha-glucosidase inhibitors, kunye ne-antioxidant compounds ziyaziwa ukulawula isifo sikashukela kwaye zifumene ingqwalasela enkulu kutshanje.Kuphononongo lwangoku, ii-algae ezine eziluhlaza (i-Chaetomorpha aerea, i-Enteromorpha intestinalis, i-Chlorodesmis, kunye ne-Cladophora rupestris) zikhethwe ukuvavanya i-alpha-amylase, i-alpha-glucosidase inhibitory, kunye nomsebenzi we-antioxidant kwi-vitro. .Umsebenzi we-Antidiabetic uvandlakanywe nge-inhibitory potential of extracts ngokuchasene ne-alpha-amylase kunye ne-alpha-glucosidase nge-spectrophotometric assays.Umsebenzi we-Antioxidant unqunywe yi-2,2-diphenyl-1-picrylhydrazyl, i-hydrogen peroxide (H2O2), kunye ne-nitric oxide scavenging assay.Uhlalutyo lwegesi lwe-chromatography-mass spectrometry (GC-MS) lwenziwa ukumisela i-compound enkulu ejongene nesenzo sayo se-antidiabetic.Phakathi kweentlobo ezahlukeneyo zesicatshulwa, isicatshulwa se-chloroform ye-C. aerea (IC50 - 408.9 μg / ml) kunye nesicatshulwa se-methanol ye-Chlorodesmis. (IC50 - 147.6 μg / ml) ibonise ukuvinjelwa okusebenzayo kwi-alpha-amylase.Izicatshulwa ziye zavavanywa kwakhona kwi-inhibition ye-alpha-glucosidase, kwaye akukho msebenzi obonwayo wafunyanwa.I-Methanol extract ye-C. rupestris ibonise umsebenzi ophawulekayo wokutshatyalaliswa kwe-radical free (IC50 - 666.3 μg / ml), ilandelwa yi-H2O2 (34%) kunye ne-nitric oxide (49%).Ngapha koko, iprofayile yeekhemikhali yiGC-MS ibonakalise ubukho bezinto eziphambili ze-bioactive.I-Phenol, i-2,4-bis (1,1-dimethylethyl) kunye ne-z, i-z-6,28-heptatriactontadien-2-enye ifunyenwe kakhulu kwisicatshulwa se-methanol ye-C. rupestris kunye ne-chloroform extract ye-C. aerea.Iziphumo zethu zibonisa ukuba i-algae ekhethiweyo ibonisa i-alpha-amylase inhibition ephawulekayo kunye nomsebenzi we-antioxidant.Ngoko ke, ukubonakaliswa kwee-compounds ezisebenzayo kunye nee-assays zayo ze-vivo ziya kuphawuleka.I-algae emine eluhlaza yakhethwa ukuvavanya i-alpha-amylase, i-alpha-glucosidase inhibitory, kunye nomsebenzi we-antioxidant kwi-vitro C. aerea kunye ne-Chlorodesmis ibonise inhibition ephawulekayo kwi-alpha-amylase, kwaye I-C. rupestris ibonise umsebenzi ophawulekayo wokutshabalalisa i-radical yamahhalaAkukho msebenzi oqatshelweyo ufunyenwe ngokuchasene ne-alpha-glucosidaseGC-MS uhlalutyo lwezicatshulwa ezisebenzayo lubonisa ubukho beekhompawundi ezinkulu ezinika ingqiqo malunga ne-antidiabetic kunye nomsebenzi we-antioxidant wezi algae.Izifinyezo ezisetyenzisiweyo: DPPH: 2,2-diphenyl-1-picrylhydrazyl, BHT: Butylated hydroxytoluene, GC-MS: Igesi chromatography-mass spectrometry.
