Iimveliso

I-4''-Propyl-3-fluorobiphenyl-4-boronic acid, eyaziwa ngokuba yi- (4-propyl-3-fluorophenyl) i-boronic acid, i-chemical compound efumene ukusetyenziswa okubalulekileyo kwiinkalo ezahlukeneyo, kuquka i-organic synthesis, isayensi yezinto, kunye nophando lwamachiza.Enye yezicelo eziphambili ze-4''-Propyl-3-fluorobiphenyl-4-boronic acid i-transition metal-catalyzed coupling reactions.Le khompawundi inokusebenza njengebhloko yokwakha i-boronic acid, evumela ukubunjwa kwe-carbon-carbon okanye i-carbon-heteroatom bonds.Ngokomzekelo, inokusetyenziswa kwi-Suzuki-Miyaura-cross-coupling reactions, apho isabela nge-aryl okanye i-vinyl halides phantsi kwe-palladium catalysis ukuvelisa i-biaryl compounds.Ezi mpendulo ze-cross-coupling zisetyenziswa ngokubanzi kwi-synthesis ye-molecule eyinkimbinkimbi yezinto eziphilayo, kubandakanywa amayeza, i-agrochemicals, kunye nezinto eziphathekayo. ibonelela ngamathuba awodwa okuphuhliswa kwezinto ezisebenzayo.Ukutshintshwa kwe-fluorine kunokuba nempembelelo ebalulekileyo kwiipropati ze-physicochemical ze-molecule, ezifana nokusabalalisa kwayo nge-elektroniki kunye ne-hydrophobicity.Ezi zakhiwo zenza izinto eziphuma kwi-4''-Propyl-3-fluorobiphenyl-4-boronic acid eziluncedo kwizicelo ezahlukeneyo, ezifana neekristale zamanzi, i-OLED (i-organic light-emitting diodes), kunye nezinye izixhobo zombane.Ngaphezu koko, iqela lepropyl kwi isakhiwo se-4''-Propyl-3-fluorobiphenyl-4-boronic acid ivumela ukuba kube lula ukukhupha, ukubonelela ukufikelela kuluhlu olubanzi lwezinto ezisebenzayo.Olu bhetyebhetye luvumela ukuhlanganiswa kweekhompawundi ezahlukeneyo ezineempawu ezilungiselelwe kunye nokusebenza.Ezi zinto ziphumayo zinokuphinda zilungiswe okanye zifakwe kwisikhokelo esikhulu semolekyuli ukuze zenze izinto ezintsonkothileyo zezinto eziphilayo, iimolekyuli ze-bioactive, kunye nezinto eziphambili.Kuphando lwamachiza, i-4''-Propyl-3-fluorobiphenyl-4-boronic acid kunye nezinto eziphuma kuyo ziye zaphononongwa njenge. abaviwa abanakho ukufunyanwa kweziyobisi.Iikhompawundi eziFluorinated zihlala zibonisa ukuzinza okuphuculweyo kwe-metabolic, ukwanda kwe-lipophilicity, kunye nokutshintsha umsebenzi webhayoloji xa kuthelekiswa nabalingane babo abangena fluorinated.Ngoko ke, ukuqaliswa kwe-athomu ye-fluorine kwi-athomu esebenzayo ye-biologically inokuphucula iimpawu zabo ze-pharmacological, ezifana ne-potency kunye nokukhetha. , isayensi yezinto, kunye nophando lwamayeza.Ikhono layo lokuthatha inxaxheba kwinguqu ye-metal-catalyzed coupling reactions, iipropati ezizodwa ezihambelana nokutshintshwa kwe-fluorine, kunye nokukwazi ukukhupha i-derivatization kwenza kube sisixhobo esixabisekileyo sokuvelisa i-molecule ze-organic complex, izinto ezisebenzayo, kunye nabaviwa abanokubakho beziyobisi.