Iimveliso

I-5-(i-Bromomethyl) -4- (4-fluorophenyl) -6-isopropyl-2--[methyl(methylsulfonyl) amino]pyrimidine i-chemical compound efumana uncedo kuphando olwahlukeneyo, amayeza, kunye nezicelo zoshishino.Le khompawundi iyaziwa ngendalo yayo eguquguqukayo kunye namandla okubambileyo ekuphuhliseni iimolekyuli ezizodwa kunye neziyobisi ngenxa yesakhiwo sayo esithile kunye namaqela asebenzayo.Kushishino lwamachiza, le khompawundi inokusebenza njengento ebalulekileyo yokuqala okanye ephakathi kwi-synthesis yamachiza ahlukeneyo. iziyobisi.Ubukho be-athomu ye-bromine, i-athomu ye-fluorine, iqela le-isopropyl, kunye nesakhiwo sendandatho ye-pyrimidine yenza kube yinto ekhangayo yokwakha i-athomu entsha eneempawu ezifunwayo.Iikhemikhali kunye nabaphandi bezonyango banokuguqula kwaye basebenze le ngqungquthela ukuzisa imisebenzi ethile okanye iimpawu zesakhiwo eziluncedo kwisenzo seyeza esijoliswe kuyo okanye iipropathi ze-pharmacokinetic eziphuculweyo.Ngaphezu koko, ubukho be-methyl kunye namaqela e-methylsulfonyl kwikhompawundi kwenza kube luncedo kwi-organic synthesis.Iqela le-methylsulfonyl linokusabela ngeendlela ezahlukeneyo, ezifana ne-nucleophilic displacement, ukupheliswa, okanye i-oxidation, evumela ukuqaliswa kwamaqela ahlukeneyo asebenzayo kwi-molecule ejoliswe kuyo.Oku kuguquguquka kwenza ukuba kuxabiseke ekudaleni iikhompawundi ezintsonkothileyo ze-organic kwindawo yelabhoratri.Ukongeza, ubume bekhompawundi buyenza ibe luncedo kwizifundo zophando.Iathom yefluorine kunye nezinye izinto ezibambeleyo zinokuba negalelo kwiipropathi ezithile zekhompawundi zomzimba okanye zekhemikhali, ziyenze kube lula ukuphanda ngeziganeko ezithile okanye njengekhompawundi yesalathiso kwizifundo ezithelekisayo.Abaphandi bahlala besebenzisa iikhompawundi ezinjalo ukuqonda ukusebenzisana kwezinto eziphilayo, ukufunda i-kinetics yokuphendula, ukuphuhlisa iindlela ezintsha zokwenziwa, okanye ukuphucula ukusebenza kweenkqubo ezikhoyo zoshishino.Kubalulekile ukuba uqaphele ukuba ukusetyenziswa okuthe ngqo kunye nokusetyenziswa okunokwenzeka kwe-5-(Bromomethyl) -4-( I-4-fluorophenyl) -6-isopropyl-2--[methyl(methylsulfonyl) amino]pyrimidine inokuhluka ngokuxhomekeka kwindawo ethile yophando okanye imboni.Izicelo ezinokuthi zekhompawundi zidlulele ngaphaya kwezo zikhankanywe ngaphambili, kwaye ukusetyenziswa kwayo kunokuphononongwa ngamachiza, i-pharmacologists, i-biochemists, kunye nezinye izazinzulu ezibandakanyekayo ekufumaneni iziyobisi, isayensi yezinto eziphathekayo, okanye uphando lwe-molecular.In summary, 5-(Bromomethyl) -4 -(4-fluorophenyl) -6-isopropyl-2--[methyl(methylsulfonyl) amino]pyrimidine i-compound eguquguqukayo ebambe isithembiso kwiyeza, iikhemikhali kunye nophando lwezoshishino.Ubume bayo obuthile kunye namaqela asebenzayo ayenza ibe sisakhiwo esinomtsalane sokwenza iimolekyuli zamachiza amatsha kunye nokuphanda ukusabela kweekhemikhali ezahlukeneyo.Izicelo ezinokuba kho zekhompawundi zibanzi, kwaye ukuphononongwa okuqhubekayo kweepropathi zayo kunokuvula indlela yenkqubela phambili kwiinkalo ezininzi zenzululwazi.