Iimveliso

I-7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-enye i-compound ene-chemical structure eyinkimbinkimbi efumana izicelo kwiinkalo ezahlukeneyo, kubandakanywa i-chemistry yamayeza kunye nophando lwe-neuroscience.Onye yezinto eziphambili zokusetyenziswa koku. i-compound ikwintsimi ye-chemistry yamayeza.Isebenza njengebhloko yokwakha okanye ephakathi kwi-synthesis yamachiza kunye nezicelo zonyango ezinokubakho.I-benzazepinone scaffold ekhoyo kule khompawundi ifana nesakhiwo esifana ne-neurotransmitters kunye neethagethi zeziyobisi, okwenza kube sisixhobo esibalulekileyo sokuyila kunye nokuphuhlisa i-compounds entsha yamachiza.Ngokuguqula isakhiwo se-7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-enye, iikhemisti zonyango zingenza izinto eziphuma kuzo ezibonisa ubudlelwane obubophekileyo kunye nokukhetha kwii-receptors ezahlukeneyo okanye i-enzymes, ezinokukhokelela ekufumaneni. yenoveli yee-agent zonyango.Ukongezelela, le khompawundi ifundwe kwinkalo yophando lwe-neuroscience.Isakhiwo se-benzazepinone sifana ne-dopamine receptor agonists ethile, eziyi-compounds ezenza i-dopamine receptors kwingqondo.I-Dopamine idlala indima ebalulekileyo ekulawuleni isimo sengqondo, intshukumo, kunye neendlela zokuvuza, iyenza ibe yinto ekujoliswe kuyo ebalulekileyo kuphuhliso lwamachiza anxulumene nokuphazamiseka kwemithambo-luvo njengesifo sikaParkinson kunye ne-schizophrenia.Ngokufunda iziphumo ze-7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-enye kunye nezinto eziphuma kuyo kwi-dopamine receptors, izazinzulu zinokufumana ulwazi malunga nomsebenzi wezi receptor kwaye zinokuthi ziphuhlise unyango olutsha lwe-neurological. ImiqathangoUxinzelelo lwe-oxidative kunye nokudumba zizinto ezisisiseko kwiimeko ezahlukeneyo ze-pathological, kubandakanya izifo zentliziyo, ukuphazamiseka kwe-neurodeergenerative, kunye nomhlaza.Abaphandi baye baphanda amandla e-compounds ukukhupha i-radicals yamahhala kunye nokuthintela iinkqubo ezivuthayo, ezinokuthi zibe nefuthe kuphuhliso lwezonyango ezijoliswe kwezi meko. -enye i-compound enezicelo ezininzi kwi-chemistry yamayeza kunye nophando lwe-neuroscience.Ubume bayo obukhethekileyo bekhemikhali buyenza ixabiseke ekudibaneni kwabaviwa beziyobisi, ngakumbi abo bajolise kwi-neurotransmitter receptors.Ngaphaya koko, iipropathi zayo ezinokubakho ze-antioxidant kunye ne-anti-ukudumba zivula amathuba okuphuhlisa unyango lwezifo ezahlukeneyo.Uphononongo oluqhubekayo lwale khompawundi kunye nezinto eziphuma kuyo kunokukhokelela ekufunyanisweni okubalulekileyo kunye nokuqhubela phambili kumacandelo amayeza kunye ne-neuroscience.