Iimveliso

I-Benzoic acid, i-2-[[1,1-dimethylethoxy) carbonyl] amino] -3-nitro-methyl ester yikhemikhali yekhemikhali enokusetyenziswa kwiindawo ezahlukeneyo, kubandakanywa amayeza kunye ne-organic synthesis. Isebenza njengesandulela okanye esiphakathi sokwenziwa kweeathom ezahlukeneyo.Ubume bayo obukhethekileyo bekhemikhali, obuquka i-benzoic acid ester edityaniswe neqela le-amino kunye ne-nitro, linika amathuba ohlengahlengiso olongezelelweyo kunye ne-derivatizations ukuphuhlisa amachiza amatsha.Oosokhemesti bamayeza banokusebenzisa le khompawundi ukwazisa iyantlukwano yesakhiwo kubaviwa bamachiza kwaye baphonononge ubudlelwane bomsebenzi wolwakhiwo (SAR) ukukhulisa iipropathi zabo zekhemesti.Ukusebenza kwe-ester kunokukhetha i-hydrolyzed ukuvelisa i-carboxylic acid ehambelanayo, enokuthi ke isebenze njengebhloko yokwakha eguquguqukayo kuphuhliso lwamachiza.Amaqela e-amino kunye ne-nitro, awaziwa ngomsebenzi wabo webhayoloji, anokunceda ekuphuhliseni amachiza ane-antimicrobial, antitumor, okanye anti-inflammatory properties.Isakhiwo sekhemikhali sekhompawundi sisenza ukuba silungele izicelo ze-organic synthesis.Iqela le-carboxylate ester linokusebenza njengeqela elikhuselayo kwimisebenzi ye-acidic, ikhusela ngexesha lokuguqulwa kweekhemikhali ezahlukeneyo.Amaqela e-amino kunye ne-nitro anokusebenza njengee-reactive moieties ukwenzela ezinye izinto eziphuma kuzo okanye ukudibanisa ukusabela, okwenza udityaniso lwee-molecule ze-organic ezintsonkothileyo.Ukuguquguquka kwale khompawundi njengento yokuqala okanye ephakathi kuyenza ixabiseke kwiikhemikhali eziphilayo ezibandakanyekayo ekudibaneni kweekhemikhali ezintle, iikhemikhali zezolimo, okanye izinto ezikhethekileyo. Kubalulekile ukuqaphela ukuba ngelixa ubume bekhemikhali bekhompawundi bucebisa usetyenziso olunokwenzeka, uphando olongezelelweyo kunye novavanyo lubalulekile. ngaphambi kokuba ukusetyenziswa kwayo okukhethekileyo kumiselwe ngokupheleleyo.Uphononongo olubanzi, kubandakanywa uvavanyo lwebhayoloji kunye novavanyo lwetyhefu, kufuneka luqhutywe ukuze kuqondwe inkangeleko yokhuseleko lwalo kwaye kumiselwe ukufaneleka kwalo kuphuhliso lwamachiza.Ukongeza, amandla ayo okwenziwa kunye nemida kufuneka iphononongwe ngezifundo ezibanzi ze-organic synthesis.Ngesishwankathelo, i-benzoic acid, i-2-[[1,1-dimethylethoxy)carbonyl]amino]-3-nitro-methyl ester ibambe amandla okusetyenziswa kumayeza kunye organic synthesis.Ubume bayo obukhethekileyo bemichiza bubonelela ngamathuba okuguqulwa kunye nokuphuma kwezinto, ezinokuphononongwa ukuphuhliswa kweziyobisi okanye ukuhlanganiswa kwe-molecule eyinkimbinkimbi.Nangona kunjalo, uphando olongezelelweyo kunye novavanyo luyimfuneko ukuze uqonde ngokupheleleyo usetyenziso olunokubakho kunye nemida kwezi nkalo.