benzyl N-({hexahydro-1H-pyrrolizin-7a-yl}methyl)carbamate hydrochloride CAS: 78449-72-6
Inombolo Yekhathalogu | XD93465 |
Igama lemveliso | benzyl N-({hexahydro-1H-pyrrolizin-7a-yl}methyl)carbamate hydrochloride |
CAS | 78449-72-6 |
Ifomu yemolekyulila | C8H15NO |
Ubunzima beMolekyuli | 141.21 |
Iinkcukacha zokuGcina | I-Ambient |
Ukucaciswa kweMveliso
Imbonakalo | Umgubo omhlophe |
uAsay | 99% imizuzu |
I-Benzyl N- ({hexahydro-1H-pyrrolizin-7a-yl} methyl) i-carbamate hydrochloride yikhemikhali yekhemikhali enezicelo ezinokubakho kwintsimi yeyeza kunye nophando lwamachiza.Iqukethe iqela le-benzyl elifakwe kwi-carbamate functionality, leyo idibaniswe ne-hexahydro-1H-pyrrolizin-7a-ylmethyl moiety.Ukongezwa kwe-hydrochloride kwikhompawundi kubonisa ubukho be-ion ye-chloride, eyenza ukunyibilika kwayo emanzini.IiCarbamates, ngokubanzi, ziyaziwa ngokubonisa imisebenzi eyahlukeneyo yebhayoloji, kubandakanya i-anticonvulsant, i-anticancer, kunye nepropathi ye-antihypertensive.Ubukho beqela le-benzyl kwi-benzyl N- ({hexahydro-1H-pyrrolizin-7a-yl} methyl) i-carbamate hydrochloride inokubonelela nge-lipophilicity ephuculweyo, evumela ukuba iwele ngokulula iimbumba zeselula.Oku kunokuba luncedo ekuhanjisweni kweziyobisi kunye nokuphucula i-bioavailability.I-Hexahydro-1H-pyrrolizin-7a-ylmethyl moiety, eyaziwa ngokuba yi-piperidinyl moiety, ifumaneka ngokuqhelekileyo kwii-bioactive compounds.IiPiperidines ziyaziwa ngendima yazo njenge-enzyme inhibitors, i-neurotransmitter modulators, kunye ne-anti-inflammatory agents.Ukudityaniswa kwale moiety kwikhompawundi kunokwandisa umsebenzi wayo webhayoloji kunye namandla onyango.Ngaphandle kokunqongophala kolwazi oluthile malunga novavanyo lwekhompawundi okanye ukusetyenziswa kweklinikhi, izicelo ezinokubakho zinokuqikelelwa ngokusekelwe kwiimpawu ezaziwayo zamaqela akhoyo.I-Benzyl N-({hexahydro-1H-pyrrolizin-7a-yl}methyl)i-carbamate hydrochloride inokuphononongwa njengomntu onokubakho kwiyeza kwiimeko ezifana nokuxhuzula, umhlaza, uxinzelelo lwegazi, okanye ukuphazamiseka kwemithambo-luvo.Isenokusetyenziswa njengebhloko yokwakha okanye ephakathi ekudityanisweni kwezinye iikhompawundi ze-bioactive. Kubalulekile ukuqaphela ukuba phambi kwaso nasiphi na isicelo esisebenzayo okanye uphando olongezelelweyo, uphando olucokisekileyo kunye novavanyo olubandakanya izifundo ze-toxicological, ukusetyenziswa kwekhemistri yamayeza, kunye novavanyo oluchasene neethagethi ezithile. kufuneka iqhutywe.Oku kuya kunceda ukucacisa ukhuseleko, ukuphumelela, kunye neendlela ezichanekileyo zesenzo se-benzyl N- ({hexahydro-1H-pyrrolizin-7a-yl} methyl) carbamate hydrochloride, ekugqibeleni ikhokelela ekusebenziseni kwayo kwinkalo yonyango.