ICapastat sulfate (Capreomycin sulfate) Cas: 1405-37-4
| Inombolo Yekhathalogu | XD92151 |
| Igama lemveliso | ICapastat sulfate (iCapreomycin sulfate) |
| CAS | 1405-37-4 |
| Ifomu yemolekyulila | C24H42N14O8·H2O4S |
| Ubunzima beMolekyuli | 752.76 |
| Iinkcukacha zokuGcina | 2 ukuya ku-8 °C |
| IKhowudi yoMrhumo eHarmonized | 29419000 |
Ukucaciswa kweMveliso
| Imbonakalo | Umgubo omhlophe |
| uAsay | 99% imizuzu |
| Iintsimbi ezinzima | 0.003% ubukhulu |
| Ukuchongwa | Uvavanyelwe iSulfate |
| pH | I-3% w / v isisombululo: 4.5-7.5 |
| I-endotoxin yebhaktheriya | 0.35 EU/mg max |
| Ilahleko ekomisweni | 10.0% ubukhulu |
| Intsalela kwi-Ignition | 3.0% ubukhulu |
| Umxholo | I-Capreomycin I: 90.0% min |
| Ubuzali | Ihambelana nomgangatho we-USP 32 |
| Amandla | Kwisiseko esomileyo: 700-1050 ug / mg |
I-Capreomycin sulfate ityuwa ye-complex ye-cyclic pentopeptides ehlukanisiwe ne-Streptomyces capreolus, eyaxelwa okokuqala kwi-1962. Ityuwa ye-sulfate iyona ndlela ixhaphakileyo yokuqulunqwa kwe-capreomycin kwaye isetyenziselwa ukusetyenziswa kwamachiza.I-complex inamacandelo amabini amakhulu, i-IA kunye ne-IB, kunye ne-exocyclic lysine residue, kunye namacandelo amancinci amabini e-delysinyl, i-IIA kunye ne-IIB.ICapreomycin sisibulali-zintsholongwane esinamandla esisebenza ngokuchasene ne-mycobateria, kunye ne-Gram positive kunye ne-negative organisms.I-Capreomycin isebenza ngokuzibophelela kwi-23S ribosomal subunit, ukuphazamisa i-protein synthesis.
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