Clopidogrel camphorsulfonate CAS: 28783-41-7
| Inombolo Yekhathalogu | XD93353 |
| Igama lemveliso | I-Clopidogrel camphorsulfonate |
| CAS | 28783-41-7 |
| Ifomu yemolekyulila | I-C26H32ClNO6S2 |
| Ubunzima beMolekyuli | 554.11 |
| Iinkcukacha zokuGcina | I-Ambient |
Ukucaciswa kweMveliso
| Imbonakalo | Umgubo omhlophe |
| uAsay | 99% imizuzu |
I-Clopidogrel camphorsulfonate yi-compound ye-pharmaceutical kunye ne-chemical formula C16H16ClNO2S·C10H16O4S.Ngokuqhelekileyo yaziwa ngokuba yiClopidogrel S-oxide camphorsulfonate okanye iClopidogrel CAMS.Le khompawundi yi-chiral derivative ye-clopidogrel, esetyenziswa ngokubanzi iyeza le-antiplatelet.Ukusetyenziswa okuphambili kwe-Clopidogrel camphorsulfonate njengento esebenzayo ekuqulunqweni kwamachiza e-antiplatelet.Isebenza ngokuthintela ukuhlanganiswa kweplatelet, ukuthintela ukubunjwa kwegazi, kunye nokunciphisa umngcipheko weziganeko ze-cardiovascular.I-compound ijolise ngokukodwa kwi-receptor ye-P2Y12 kwiiplatelet, ngaloo ndlela ivimbela inkqubo yokuvuselela kunye nokuvimbela ukuhlanganiswa kweeplatelet.Le ndlela yokusebenza yenza ukuba i-Clopidogrel camphorsulfonate isebenze ekukhuseleni i-arterial thrombosis kunye nokunciphisa iziganeko ezingathandekiyo ze-cardiovascular, kubandakanywa ukuhlaselwa kwentliziyo kunye ne-stroke.Emva kokuba idliwe, iguqulelwa kwi-metabolism kwisibindi, okubangela ukubunjwa kwe-metabolite esebenzayo.Le metabolite esebenzayo ke ibophelela ngokungenakuguquleka kwi-P2Y12 receptor, isebenzise iziphumo zayo ze-antiplatelet ixesha elide.Kwinkqubo yonyango, i-Clopidogrel camphorsulfonate idla ngokumiselwa izigulana ezine-acute coronary syndromes, ezifana ne-angina engazinzanga kunye ne-myocardial infarction, okanye abo baye batyhubela i-coronary coronary. ungenelelo (PCI) ngokubeka i-stent.Kwakhona kusetyenziswa ngokubanzi ukukhusela ukwenzeka kweziganeko ze-thrombotic kwizigulane ezinembali ye-stroke okanye isifo se-peripheral artery.Ukusetyenziswa kweClopidogrel camphorsulfonate ihlala idityaniswa kunye nedosi ephantsi ye-aspirin yokwandisa unyango lwe-antiplatelet. Kubalulekile ukuqaphela ukuba i-Clopidogrel camphorsulfonate kufuneka isetyenziswe kuphela phantsi kweliso lonyango lwezempilo, njengoko inokusebenzisana namanye amayeza okanye ibe nokuchasana kwezinye. abantu abagulayo.Umthamo kunye nobude bonyango lunokwahluka ngokuxhomekeka kwimeko yonyango yomntu, kwaye ukubeka iliso rhoqo ekusebenzeni kweplatelet kunye novavanyo lwegazi kunokuba yimfuneko ukuze kuqinisekiswe eyona mpembelelo yonyango. ngakumbi ezo zibandakanya i-arterial thrombosis.Iimpawu zayo ze-antiplatelet kunye nokuthintela okukhethiweyo kwe-receptor ye-P2Y12 yenza ukuba iyeza elisebenzayo lokunciphisa umngcipheko weziganeko ezimbi ze-cardiovascular.Nangona kunjalo, njengayo nayiphi na i-compound yamayeza, isilumkiso kufuneka sisetyenziswe ekusetyenzisweni kwayo, kwaye izigulane kufuneka zihambelane neengcebiso zabo zomboneleli wezempilo kunye nesikhokelo.
