I-Curcumin Cas: 458-37-7
Inombolo Yekhathalogu | XD91961 |
Igama lemveliso | I-Curcumin |
CAS | 458-37-7 |
Ifomu yemolekyulila | C21H20O6 |
Ubunzima beMolekyuli | 368.38 |
Iinkcukacha zokuGcina | 2-8°C |
IKhowudi yoMrhumo eHarmonized | 29145000 |
Ukucaciswa kweMveliso
Imbonakalo | umgubo orenji |
uAsay | 99% imizuzu |
Indawo yokunyibilika | 183 °C |
Indawo yokubilisa | 418.73°C (uqikelelo olurhabaxa) |
ukuxinana | 0.93 |
ukuxinana komphunga | 13 (vs umoya) |
isalathiso se-refractive | 1.4155-1.4175 |
Fp | 208.9±23.6 °C |
ukunyibilika | i-ethanol: 10 mg/mL |
pka | 8.09(nge-25℃) |
Ivumba | Ayinavumba |
PH Uluhlu | Mthubi (7.8) ukuya kubomvu-mdaka (9.2) |
Ukunyibilika kwamanzi | Inyibilika kancinane (kushushu) |
Ikhompawundi ye-phenolic yendalo.I-arhente echasene ne-tumor ene-anti-inflammatory kunye ne-anti-oxidant properties.Yenza i-apoptosis kwiiseli zomhlaza kwaye inqanda umsebenzi we-phorbol ester-induced protein kinase C (PKC).Kuxelwe ukuthintela ukuveliswa kwee-cytokines ezivuthayo nge-peripheral blood monocytes kunye ne-alveolar macrophages.I-inhibitor enamandla ye-EGFR tyrosine kinase kunye ne-IkB kinase.Ivimbela i-nitric oxide synthase (iNOS), i-cycloxygenase kunye ne-lipoxygenase.Ukungena ngokulula kwi-cytoplasm yeeseli, ziqokelela kwizakhiwo ze-membranous ezifana ne-plasma membrane, i-endoplasmic reticulum kunye nemvulophu yenyukliya.
I-Curcumin yinqununu ye-curcuminoid ye-Indian spice turmeric eyaziwayo, ilungu lentsapho ye-ginger (Zingiberaceae).I-curcuminoids i-polyphenols kwaye inoxanduva lombala ophuzi we-turmeric.