I-Cyclosporin A CAS: 59865-13-3 I-crystalline powder emhlophe 99%
Inombolo Yekhathalogu | XD90346 |
Igama lemveliso | Cyclosporin A |
CAS | 59865-13-3 |
Ifomula yeemolekyuli | I-C62H111N11O12 |
Ubunzima beMolekyuli | 1202.61 |
Iinkcukacha zokuGcina | 2 ukuya ku-8 °C |
IKhowudi yoMrhumo eHarmonized | 29419000 |
Ukucaciswa kweMveliso
Isivavanyi | 99% |
Imbonakalo | Umgubo omhlophe wekristale |
IBanga | USP 35 |
Ukungcola | Ubumdaka bubonke: 0.6% ubukhulu, Ubuninzi bokungacoceki okuNye: 0.2% |
Iintsimbi ezinzima | 20ppm ubukhulu |
I-acetone | 10ppm |
Ilahleko ekomisweni | 2.0% ubukhulu |
Ubushushu boGcino | +4% |
Imbonakalo yesisombululo | Isisombululo njengoko kuchaziwe kwi-EPIV |
IPetroleum ether izinto ezinyibilikayo | 31ppm |
Iipropati: Umgubo omhlophe okanye omhlophe, ongenavumba kwaye awunancasa.Inyibilika ngokulula kwi-methanol, ethanol okanye kwi-acetonitrile, inyibilika ngokulula kwi-ethyl acetate, inyibilika kwi-acetone okanye i-ether, kwaye phantse ayinyibiliki emanzini.Ukujikeleza okuthe ngqo kwale mveliso kunqunywe yincwadi yeekhemikhali, kwaye ichithwe kwi-methanol ukwenza isisombululo esiqulethe i-10 mg nge-1 ml.Ukujikeleza okuthe ngqo ngu-182 ° ukuya -192 °.Ukusetyenziswa: uphando lwe-biochemical.Ukuthintela iindlela zokubonisa i-T cell receptor
Le mveliso luhlobo olutsha lwe-immunosuppressant.Yinto ye-cyclic polypeptide eyenziwe ngee-amino acids ezilishumi elinanye.Icinezela i-humoral kunye ne-cell-delivered immune function ngaphandle kokucinezela umongo wethambo kunye nokunciphisa inani leeseli ezimhlophe zegazi.Inokuthintela ukugatywa kwezicubu ezitshintshiweyo okanye i-organ Chemicalbook.Isetyenziselwa ukutshintshwa kwezintso, isibindi, imiphunga kunye nentliziyo.Ukongeza, inefuthe elithile lokunyanga kwizifo ezizimelayo, kunye ne-schistosomiasis, i-malaria, isifo seswekile, i-AIDS, njl., kunye neempawu ezichasayo.
Kunyango lwe-leukemia, umhlaza, ukutshintshwa kwezintso, isifo sephepha, njl.