I-D-Glutamic acid CAS: 6893-26-1 99% Umgubo omhlophe
| Inombolo Yekhathalogu | XD90313 |
| Igama lemveliso | D-Glutamic acid |
| CAS | 6893-26-1 |
| Ifomula yeemolekyuli | C5H9NO4 |
| Ubunzima beMolekyuli | 147.13 |
| Iinkcukacha zokuGcina | I-Ambient |
| IKhowudi yoMrhumo eHarmonized | 29224200 |
Ukucaciswa kweMveliso
| Imbonakalo | Umgubo omhlophe wekristale |
| Isivavanyi | 99% |
| Ukujikeleza okuthe ngqo | -31 ukuya -32.2 |
| Iintsimbi ezinzima | <10ppm |
| AS | <1ppm |
| pH | 3 - 3.5 |
| SO4 | <0.020% |
| Fe | <10ppm |
| Ilahleko ekomisweni | <0.20% |
| Intsalela kwi-Ignition | <0.10% |
| NH4 | <0.02% |
| Cl | <0.02% |
| Imeko yesisombululo | >98% |
I-γ-Glutamyltranspeptidases (γ-GTs) iqhawula i-γ-glutamyl amide bond ye-glutathione kwaye idlulisele iqela elikhutshiweyo le-γ-glutamyl kumanzi (i-hydrolysis) okanye i-amino acids eyamkelekileyo (transpeptidation).Ezi enzymes zifumaneka kuyo yonke indawo zidlala indima ephambili kwi-biosynthesis kunye nokuthotywa kwe-glutathione, kunye ne-xenobiotic detoxification.Apha sixela i-3Å isisombululo sekristale isakhiwo se-Bacillus licheniformis γ-GT (BlGT) kunye neso bunzima bayo kunye ne-l-Glu.Ulwakhiwo lweX-reyi luqinisekisa ukuba i-BlGT yeye-N-terminal nucleophilic hydrolase superfamily kwaye ityhila ukuba iproteni inendawo evulekileyo ecandekileyo ecandekileyo efana naleyo ibixelwe kwi-enzyme ye-homologous evela kwi-Bacillus subtilis, kodwa yahlukile kwezo zijongwe ngabantu γ-GT kunye ye-γ-GTs evela kwezinye ii-microorganisms.Idatha icebisa ukuba ukubophelela kwe-l-Glu kubangela ukucwangciswa kwakhona kwe-C-terminal umsila we-BlGT enkulu kunye nokuvumela ukuchongwa kweqela leentsalela ze-asidi ezinokuthi zibandakanyeke ekuqapheliseni i-ion yensimbi.Indima yezi ntsalela kuzinzo oluhambelanayo lwe-BlGT iye yaphononongwa ngokubonakalisa i-autoprocessing, umsebenzi we-enzymatic, iikhemikhali kunye ne-thermal denaturation ye-Ala enye entsha eguqulweyo.Iziphumo zibonisa ukuba ukutshintshwa kwe-Asp568 nge-Ala kuchaphazela ukusetyenzwa ngokuzenzekelayo kunye nozinzo lweprotheyini.
