Geldanamycin Cas: 30562-34-6
Inombolo Yekhathalogu | XD92264 |
Igama lemveliso | Geldanamycin |
CAS | 30562-34-6 |
Ifomu yemolekyulila | I-C29H40N2O9 |
Ubunzima beMolekyuli | 560.64 |
Iinkcukacha zokuGcina | -15 ukuya -20 °C |
IKhowudi yoMrhumo eHarmonized | 29419000 EXP 2941900000 IMP |
Ukucaciswa kweMveliso
Imbonakalo | Umgubo otyheli |
uAsay | 99% imizuzu |
I-Geldanamycin sisibulala-ntsholongwane esinamandla esilwa ne-antitumor esebenzayo kwi-nanomolar concentration ngokuchasene nemigca yeeseli ezingama-60.Ibophelela ngokuthe ngqo kwiprotheyini yokothuka ubushushu i-Hsp90 kunye ne-endoplasmic reticulum homologue GP96, kwaye ngaloo ndlela iphazamisana nokuvuthwa kweeprotheni kunye nokuphendula koxinzelelo lweselula.Ukongeza, yi-inhibitor enamandla yentsapho ye-nyukliya ye-receptors ye-hormone.
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