L-Arginine CAS: 74-79-3 99% Iikristale ezimhlophe okanye i-crystalline powder
| Inombolo Yekhathalogu | XD90323 |
| Igama lemveliso | L-Arginine |
| CAS | 74-79-3 |
| Ifomula yeemolekyuli | I-C6H14N4O2 |
| Ubunzima beMolekyuli | 174.20 |
| Iinkcukacha zokuGcina | I-Ambient |
| IKhowudi yoMrhumo eHarmonized | 29252900 |
Ukucaciswa kweMveliso
| Imbonakalo | Iikristale ezimhlophe okanye i-crystalline powder |
| Isivavanyi | 99% |
| Ukuchongwa | Ukufunxwa kwe-infrared |
| Ilahleko ekomisweni | ≤ 0.5% |
| Ukucoceka kweChromatographic | Akukho ngaphezulu kwe-0.5% yokungcola komntu okufunyenweyo; Akukho ngaphezulu kwe-2.0% yokungcola okupheleleyo kufunyenwe |
| Intsalela kwi-Ignition | ≤ 0.3% |
| Iintsimbi ezinzima ( PB ) | ≤ 0.0015% |
| Intsimbi (njenge-Fe) | ≤ 0.003% |
| I-Sulfate (njenge-SO4) | ≤ 0.03% |
| Ibanga le-Usp | USP 33 |
| I-Chloride (CI) | ≤ 0.05% |
| Ukujikeleza ngokuthe ngqo [ α ] D 2 5 | +26,3 ° ~ +27,7 ° |
Indlela ye-Mycobacterium smegmatis G (MbsG), i-l-lysine monooxygenase exhomekeke kwi-flavin, yaphandwa phantsi kweemeko ezizinzileyo kunye neemeko zokusabela ngokukhawuleza kusetyenziswa i-primary and solvent kinetic isotope iziphumo, i-substrate analogs, i-pH kunye ne-solvent viscosity effects as mechanistic probes.Iziphumo zibonisa ukuba i-l-lysine ibophelela phambi kwe-NAD (P) H, ekhokelela ekunciphiseni umlinganiselo oqhubekayo wokunciphisa i-flavin.Ukubopha i-l-lysine ayinayo impembelelo kwisantya se-flavin oxidation, eyenzeka kwinkqubo yenyathelo elinye ngaphandle kokuqwalaselwa kwe-C4a-hydroperoxyflavin ephakathi.Iziphumo ezifanayo zagqitywa ngee-analog ezininzi ze-substrate.I-Flavin oxidation i-pH ezimeleyo ngelixa i-kcat/Km kunye ne-kred/KD pH iiprofayili ze-NAD(P)H zibonisa amaxabiso e-pKa enye engu-∼6.0, nomsebenzi owandisiweyo njengoko i-pH iyancipha.Kwi-pH ephantsi, i-enzyme iyancipha ngakumbi, ivelisa ngakumbi i-hydrogen peroxide kunye ne-superoxide.Utshintshiselwano lwe-Hydride lunciphisa ngokuyinxenye isantya kwi-pH engathathi ntweni kwaye iba sisithintelo esingaphezulu kwi-pH ephantsi.Impembelelo ye-viscosity ye-solvent eguqukileyo kwi-kcat/Km ye-NAD(P)H ibonwe kwi-pH engathathi hlangothi ngelixa isiphumo se-solvent se-viscosity esiqhelekileyo sabonwa kwi-pH ephantsi.Ngokubambisana, iziphumo zibonisa indlela ekhethekileyo apho umlinganiselo wokukhawulela kunye ne-pH-sensitive conformational utshintsho lwenzeka kwi-reductive half-reaction, echaphazela ukusebenza kakuhle kwe-lysine hydroxylation.
