Iimveliso

I-Lithium trifluoromethanesulfonate, ekwabizwa ngokuba yi-LiOTf, sisixhobo esisebenzayo esibalulekileyo kunye ne-catalyst kwi-organic synthesis.Ityuwa eyenziwe ngokudibanisa i-lithium cations (Li +) kunye ne-trifluoromethanesulfonate anions (OTf-).I-LiOTf isetyenziswa ngokubanzi kwiimpendulo zeekhemikhali ezahlukeneyo ngenxa yeempawu zayo ezizodwa kunye nokukwazi ukuququzelela utshintsho olufunekayo.Enye yezicelo eziphambili ze-lithium trifluoromethanesulfonate njenge-catalyst ye-Lewis acid.Iyakwazi ukusebenzisa amaqela ahlukeneyo asebenzayo kunye ne-substrates, ukukhuthaza ukuphendula okubandakanya ukubunjwa kwamabhondi amatsha.I-LiOTf iyasebenza kakhulu ekwenzeni kusebenze iibhondi ze-carbon-oxygen (CO), ezifana ne-acetalization reaction, apho iququzelela ukusekwa kwee-acetals ezivela kwiialkoholi.Inokuthi isebenze ezinye iibhondi ezine-heteroatom, ezifana ne-carbon-nitrogen (CN) bond, eyenza ukubunjwa kwe-amides okanye imines.Ukusetyenziswa kwe-LiOTf njenge-catalyst ivumela iimeko zokusabela ezithambileyo, iimfuno ezisezantsi zamandla, kunye nokuphuculwa kokukhethwa.LiOTf ikwasetyenziswa njengomthombo we-lithium cations kwiimpendulo ezahlukeneyo.I-Lithium yi-ion yesinyithi eluncedo enokuthi ithathe inxaxheba kuluhlu lweempendulo, ezifana ne-metal-catalyzed cross-coupling reactions kunye ne-nucleophilic substitution reactions.I-LiOTf ibonelela ngomthombo ofanelekileyo nofumaneka lula we-lithium kolu tshintsho.Ukongezelela, i-anion ye-trifluoromethanesulfonate inokusebenza njenge-counterion, ukulinganisa intlawulo ye-lithium cation kunye nokuzinzisa i-intermediates esebenzayo.Ngaphezu koko, i-LiOTf ifumana izicelo kwi-synthetic chemistry ukuze ikwazi uku-solubilize kunye nokuzinzisa abaphakathi abasebenzayo.Ingasebenza njengesinyibilikisi esilungelelanisayo, iququzelele ukusabela okubandakanya iinguqu zesinyithi zecatalysts okanye ezinye iintlobo ezisebenzayo.Ngaphaya koko, i-LiOTf ihlala isetyenziswa njenge-electrolyte kwiibhetri ze-lithium-ion ngenxa yozinzo kunye ne-ionic conductivity ephezulu. Kubalulekile ukuqaphela ukuba i-LiOTf kufuneka iphathwe ngononophelo ngenxa yokuphinda isebenze kunye nokutsha kwayo.Kufuneka igcinwe kwindawo epholileyo, eyomileyo, kude nokufuma kunye nemithombo yobushushu.Njengezinye iityuwa ze-lithium, i-LiOTf ibeka umngcipheko wokubola kwe-thermal kwaye inokuvelisa i-fumes enetyhefu xa ibonakaliswe kubushushu obuphezulu.I-acidity yayo ye-Lewis, ukukwazi ukubonelela nge-lithium cations, kunye neempawu zokunyibilikisa kwenza ukuba ixabiseke kwiinguqu ezahlukeneyo zeekhemikhali.Nangona kunjalo, imilinganiselo efanelekileyo yokuphatha kunye nokugcinwa kufuneka kuthathwe ukuqinisekisa ukusetyenziswa kwayo ngokukhuselekileyo.