Iimveliso

I-Losartan liyeza elikwiklasi yamachiza eyaziwa ngokuba yi-angiotensin II receptor blockers (ARBs).Ngokuyintloko isetyenziselwa ukunyanga uxinzelelo lwegazi oluphezulu (uxinzelelo lwegazi) kunye neentlobo ezithile zeemeko zentliziyo.I-Hypertension yimeko eqhelekileyo ebonakaliswe ngamanqanaba aphezulu oxinzelelo lwegazi.Ukuba ayiphathwa, kunokukhokelela kwiingxaki zempilo ezinzulu ezifana nesifo senhliziyo, isifo sohlangothi, kunye neengxaki zezintso.I-Losartan isebenza ngokuthintela isenzo sehomoni ebizwa ngokuba yi-angiotensin II, ethintela imithambo yegazi kwaye ibangele ukuba uxinzelelo lwegazi lunyuke.Ngokuthintela le hormone, i-losartan inceda ukuphumla kunye nokwandisa imithwalo yegazi, ngaloo ndlela inciphisa uxinzelelo lwegazi.Ngaphezu kokunyanga uxinzelelo lwegazi, i-losartan nayo inenzuzo kwiimeko ezithile zentliziyo, ezifana nokungaphumeleli kwentliziyo kunye ne-hypertrophy ye-ventricular yasekhohlo.Inokukunceda ukuphucula iimpawu, ukuphucula ukusebenza kwentliziyo, kunye nokunciphisa umngcipheko weziganeko zentliziyo kwizigulane ezinezi meko.Ngaphezu koko, i-losartan ifunyenwe ibe nefuthe lokukhusela izintso kubantu abanesifo sikashukela sohlobo lwe-2 kunye ne-nephropathy yesifo sikashukela (isifo sezintso).Inokucothisa ukuqhubela phambili komonakalo wezintso, ukunciphisa i-proteinuria (iprotheni engaphezulu kumchamo), kwaye incede ukugcina ukusebenza kwezintso kwaba bantu.Ngokuqhelekileyo ithathwa ngomlomo kanye ngemini, kunye okanye ngaphandle kokutya.Kubalulekile ukulandela idosi emiselweyo kunye nemiyalelo enikwa yingcali yezempilo. Njengalo naliphi na iyeza, i-losartan inokuba neziphumo ebezingalindelekanga.Iziphumo ebezingalindelekanga eziqhelekileyo zinokubandakanya isiyezi, ukudinwa, intloko ebuhlungu, kunye nokuphazamiseka kwesisu.Kucetyiswa ukuba uxele nayiphi na imiphumo emibi okanye eqhubekayo kumboneleli wezempilo.Ngokufutshane, i-losartan i-angiotensin II receptor blocker esetyenziswa ngokuqhelekileyo kunyango lwe-hypertension, iimeko zentliziyo ezifana nokuhluleka kwentliziyo, kunye ne-nephropathy yesifo sikashukela.Ngokuthintela isenzo se-angiotensin II, i-losartan inceda ukuphumla kunye nokwandisa imithambo yegazi, ngaloo ndlela inciphisa uxinzelelo lwegazi kunye nokuphucula ukusebenza kwentliziyo.Liyeza elixabisekileyo ekulawuleni ezi meko kwaye kufuneka lithathwe njengoko kuyalelwa ngumsebenzi wezempilo.