I-Neomycin Sulfate Cas: 1405-10-3
| Inombolo Yekhathalogu | XD91890 |
| Igama lemveliso | Neomycin sulfate |
| CAS | 1405-10-3 |
| Ifomu yemolekyulila | I-C23H48N6O17S |
| Ubunzima beMolekyuli | 712.72 |
| Iinkcukacha zokuGcina | 2-8°C |
| IKhowudi yoMrhumo eHarmonized | 29419000 |
Ukucaciswa kweMveliso
| Imbonakalo | Umgubo omhlophe |
| uAsay | 99% imizuzu |
| Indawo yokunyibilika | >187°C (ngoDisemba) |
| alpha | D20 +54° (c = 2 kwi-H2O) |
| isalathiso se-refractive | 56 ° (C=10, H2O) |
| Fp | 56℃ |
| ukunyibilika | I-H2O: 50 mg / mL Njengesisombululo sesitokhwe.Izisombululo zesitokhwe kufuneka zihluzwe iintsholongwane kwaye zigcinwe kwi-2-8°C.Izinzile kwi-37 ° C iintsuku ezi-5. |
| PH | 5.0-7.5 (50g/l, H2O, 20℃) |
| Ukunyibilika kwamanzi | Inyibilika emanzini |
| Uzinzo | Izinzile.Ayihambelani ne-oxidizing agents ezinamandla. |
I-NEOMYCIN SULFATE sisibulali-zintsholongwane esibizwa ngokuba yi-aminoglycoside efumaneka kumayeza amaninzi.I-NEOMYCIN SULFATE isetyenziswe njengendlela yokuthintela i-hepatic encephalopathy kunye ne-hypercholesterolemia.
I-NEOMYCIN SULFATE yi-antibiotic ye-aminoglycoside eveliswa ngu-S. fradiae evimbela ukuguqulelwa kweprotheni ngokuzibophelela kwi-subunit encinci ye-ribosomes ye-prokaryotic.Ivimba i-voltage-sensitive Ca2+ channels kwaye iyi-inhibitor enamandla yokukhululwa kwe-skeletal muscle sarcoplasmic reticulum Ca2 +.I-NEOMYCIN SULFATE iboniswe ukuba inqanda i-inositol phospholipid, i-phospholipase C, kunye nomsebenzi we-phosphatidylcholine-phospholipase D (IC50 = 65 μM).Isebenza kakhulu ngokuchasene ne-Gram-positive kunye ne-Gram-negative bacteria kwaye iqhele ukusetyenziselwa ukuthintela ukungcoliseka kwebhaktiriya kwiinkcubeko zeeseli.
I-Neomycin sulfate sisibulali-zintsholongwane (inokusetyenziswa ngokufanelekileyo ngokuchasene neebhaktheriya ezininzi ezibangela izifo zesikhumba, zamehlo kunye nendlebe yangaphandle);i-antibiotiki ebanzi kwiikhrimu ze-topical, i-powders, i-ointments, i-eye kunye ne-ear drops;i-antibiotiki yenkqubo kunye nokukhuthaza ukukhula kusetyenziso lwezilwanyana.
