Oxytetracycline HCL Cas: 2058-46-0
| Inombolo Yekhathalogu | XD91891 |
| Igama lemveliso | I-Oxytetracycline HCL |
| CAS | 2058-46-0 |
| Ifomu yemolekyulila | I-C22H25ClN2O9 |
| Ubunzima beMolekyuli | 496.89 |
| Iinkcukacha zokuGcina | 0-6°C |
| IKhowudi yoMrhumo eHarmonized | 29413000 |
Ukucaciswa kweMveliso
| Imbonakalo | Umgubo wekristale otyheli |
| uAsay | 99% imizuzu |
| Indawo yokunyibilika | 180°C |
| alpha | -188～-200°(D/20℃)(c=1,0.1mol/l HCl) (ibalwe ngokomisiweyo) |
| ukunyibilika | Inyibilika ngokukhululekileyo emanzini, inyibilika kancinci kwi-ethanol (ipesenti ezingama-96).Izisombululo emanzini ziyaphazamiseka xa zimile, ngenxa yokuna kwe-oxytetracycline. |
| PH | 2.0～3.0 (10g/l, 25℃) |
| Ukunyibilika kwamanzi | >100 g/L |
| λmax | 360nm(H2O)(lit.) |
| Inovakalelo | Ukukhanya okunovelwano |
I-Oxytetracycline hydrochloride yityuwa elungiselelwe kwi-oxytetracycline ithatha inzuzo yeqela elisisiseko le-dimethylamino elikhupha ngokukhawuleza ukwenza ityuwa kwi-hydrochloric acid solutions.I-hydrochloride yindlela ekhethwayo yokwenziwa kwezicelo zamachiza.Njengazo zonke i-tetracyclines, i-oxytetracycline ibonisa i-antibacterial spectrum ebanzi kunye nomsebenzi we-antiprotozoan kwaye yenza ngokuzibophelela kwi-30S kunye ne-50S ye-ribosomal sub-units, ukuvimba iprotheni synthesis.
Amachiza okubulala iintsholongwane ahlukanisiwe kwiimveliso ze-actinomycete, iStreptomyces rimosus, ekhuliswe kwindawo efanelekileyo.I-antibacterial.
I-Oxytetracycline sisibulali-zintsholongwane esiboniswa kunyango losulelo olubangelwa yiGram positive kunye neGram negative microorganisms ezifana neMycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, kunye neDiplococcus pneumoniae.Isetyenziswe kwizifundo kwi-oxytetracycline-resistance gene (otrA).I-Oxytetracycline hydrochloride isetyenziselwa ukufunda i-phagosome-lysosome (PL) fusion kwii-P388D1 cells1 kunye ne-antibiotic susceptibility of Mycoplasma bovis isolate.
