I-PHENYL-1-THIO-β-D-GALACTOPYRANOSIDE Cas: 16758-34-2 95% Umgubo omhlophe
Inombolo Yekhathalogu | XD90049 |
Igama lemveliso | IPHENYL-1-THIO-β-D-GALACTOPYRANOSIDE |
CAS | 16758-34-2 |
Ifomula yeemolekyuli | I-C12H16O5S |
Ubunzima beMolekyuli | 272.32 |
Iinkcukacha zokuGcina | I-Ambient |
Ukucaciswa kweMveliso
Imbonakalo | Umgubo omhlophe |
Isivavanyi | 95% imizuzu |
yokugcinaTemp. | 2-8°C |
ukubonaAumsebenzi | [α]22/D -48.0°,c = 0.5% |
Mp | 93-98 °C |
Ukubophelela kwe-phenyl endaweni ye-1-thio-β-D-galactopyranosides kwi-β-D-galactosidase ukusuka ku-e.
Ukubophelela koluhlu lwe-phenyl 1-thio-β-D-galactopyranosides endaweni esebenzayo ye-β-D-galactosidase esuka kwi-E. coli iphandiwe.I-inhibition constants kunye ne-standard standard free energy transfer ΔG ° (K1) yafaniswa ne-partition coeficients kunye ne-ΔG ° (1-octanol) ixabiso lale molekyuli ze-inhibitor kwindlela ye-1-octanol-water system.Bonke ubungqina obukhoyo bubonisa ukuba iqela le-aglycon le-inhibitor liboshwe kwindawo esebenzayo engabonakaliyo, amandla e-hydrophobic.Unxulumano phakathi kwe-ΔG ° (K1) kunye ne-ΔG ° (1-octanol) ayifumanekanga kulo lonke uthotho, kodwa kuluhlu oluncinci olulula.Mhlawumbi, inkqubo ye-octanol ayiphelelanga kakhulu imodeli yengingqi ye-hydrophobic kwindawo esebenzayo ye-β-D-galactosidase.