Iplatinam(IV) chloride Cas:13454-96-1 Umgubo obomvu-brown
Inombolo Yekhathalogu | XD90688 |
Igama lemveliso | IPlatinum (IV) ikloridi |
CAS | 13454-96-1 |
Ifomula yeemolekyuli | I-Cl4Pt |
Ubunzima beMolekyuli | 336.89 |
Iinkcukacha zokuGcina | Gcina ngaphantsi +30°C |
IKhowudi yoMrhumo eHarmonized | 28439090 |
Ukucaciswa kweMveliso
Imbonakalo | Umgubo obomvu-mdaka |
Isivavanyi | 99% |
Damandla | 4.303 |
Indawo yokunyibilika | 370℃ |
logP | 2.75550 |
Ukwakha i-carrier carrier kunye ne-gene vector ye-PEG-PEI-Pt.Polyethyleneglycol (PEG) idibene ne-polyethylenimine (PEI 600) kunye ne-platinum tetrachloride;I-PEG-PEI-Pt complex yenziwe kwi-ethanol.I-complex ibonakaliswe yi-XRD, i-UV-VIS kunye ne-FT-IR kunye ne-DNA condensation yavavanywa nge-electrophoretic mobility shift assay.Ubume beseli buhlolwe nguvavanyo lwe-MTT kwi-Hela, B16, A293 kunye neeseli ze-COS-7 kunye nokusebenza kakuhle kwe-vitro transfection kulinganiswe kwiiseli ze-A293 kunye ne-B16. Isakhiwo se-PEG-PEI-Pt sibonakaliswe yi-XRD, UV-VIS kunye ne-FT. -IR.I-PEG-PEI-Pt i-complex yakwazi ukubopha i-DNA kwi-N / P ubunzima be-0.4: 1;i-complex ibonise i-cytotoxicity kwi-Hela kunye neeseli ze-B16.I-complex yayine-transfection esebenzayo ephezulu kwiiseli ze-A293 kunye ne-B16 kune-PEI 600. I-novel carrier carrier kunye ne-gene vector ye-PEG-PEI-Pt yakhiwe ngempumelelo.