S)-(+)-Camptothecin Cas: 7689-03-4
Inombolo Yekhathalogu | XD92150 |
Igama lemveliso | S)-(+)-Camptothecin |
CAS | 7689-03-4 |
Ifomu yemolekyulila | I-C20H16N2O4 |
Ubunzima beMolekyuli | 348.35 |
Iinkcukacha zokuGcina | 2-8°C |
IKhowudi yoMrhumo eHarmonized | 29397990 |
Ukucaciswa kweMveliso
Imbonakalo | Okumhlophe-mhlophe ukuya kumgubo omthubi |
uAsay | 99% imizuzu |
Indawo yokunyibilika | 261 - 265 Deg C |
Ukujikeleza okuthe ngqo | +29 ukuya +31 |
Ilahleko ekomisweni | 1% max |
Ubunyulu HPLC | >99% |
1. Amachiza okulwa nomhlaza.Ngomhlaza wesisu, umhlaza wekoloni, umhlaza we-rectal, intloko kunye nentamo umhlaza wecylinroid kunye nomhlaza wesinyi
2. Kunyango lomhlaza wesisu, umhlaza wamathumbu, uhlobo olungapheliyo lwegranulocytic kunye ne-acute leukemia, njl.
3. Ibophelela ngokungenakujikwa kwi-DNA topoisomerase I complex, echaphazela inkqubo yomjikelo weseli.
4. I-Camptothecin yayiye yahlukaniswa ekuqaleni kwiziqu zeCamptotheca acuminata kwaye yabonisa umsebenzi wokulwa ne-leukemia / anti-tumor.Ibophelela ngokungenakujikwa kwi-DNA topoisomerase I complex, inqanda ukudityaniswa kwe-DNA emva kokucheba i-topoisomerase I, kwaye itshixe i-enzyme kunye ne-DNA ngendlela ye-covalent bond.
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