SYBR GREEN I Nucleic Acid Gel Stain Cas: 163795-75-3 99% Solid
| Inombolo Yekhathalogu | XD90236 |
| Igama lemveliso | SYBR GREEN I Nucleic Acid Gel Stain |
| CAS | 163795-75-3 |
| Ifomula yeemolekyuli | I-C32H37N4S |
| Ubunzima beMolekyuli | 509.728 |
| Iinkcukacha zokuGcina | -20°C |
Ukucaciswa kweMveliso
| Imbonakalo | Umgubo omhlophe |
| Isivavanyi | 99% |
I-Flow cytometry yindlela enenjongo yokwenza uvavanyo lwe-in vitro antimalarial sensitivity kunye nokwandisa amandla okusetyenziswa kwiindawo zentsimi.Sivavanye ukuchaphazeleka kwe-in vitro kumachiza asixhenxe e-anti-malarial kwi-40 entsha ye-P. falciparum intsimi yodwa nge-flow cytometry method (FCM), i-colorimetric LDH-based ELISA: DELI), kunye nohlalutyo oluqhelekileyo lwesilayidi se-microscopic sokukhula.Kwi-FCM, i-184/280 (66%) i-assays idibene ne-analytical acceptance criteria, xa kuthelekiswa ne-166/280 (59%) ye-DELI.Kwakukho isivumelwano esihle phakathi kwe-FCM kunye ne-microscopy, ngelixa i-DELI ithande ukuvelisa i-half-maximal inhibition constants (IC50s) kune-FCM, kunye ne-bias jikelele ye-2.2-fold (uthelekiso lwe-Bland-Altman).Amaxabiso e-artesunate kunye ne-dihydroartemisinin aye achaphazeleka kakhulu.Ukunyuka okumangalisayo komqondiso kwiindawo eziphezulu kakhulu ze-mefloquine kunye neekhompawundi ezinxulumene nazo zaphawulwa ngakumbi ngovavanyo lwe-DELI, ebonisa ukuba iziphumo ezijoliswe kuyo kwimveliso ye-LDH zinokuba noxanduva.Ilahleko yophawu lweFCM ngenxa yohlaziyo okanye ukukhula kancinci kuye kwabonwa kwinani elincinci leisampulu.Ezi ziphumo zandisa umsebenzi wangaphambili wokusetyenziswa kwe-cytometry yokuhamba ukuze kuqinisekiswe ukuchaphazeleka kwe-antimalarial ngokwenani leesampuli, uluhlu lwamachiza, kunye nokuthelekisa nezinye iindlela.
