I-Vancomycin hydrochloride CAS: 1404-93-9 99% Imhlophe okanye i-tan ukuya kumgubo opinki
| Inombolo Yekhathalogu | XD90370 |
| Igama lemveliso | Vancomycin hydrochloride |
| CAS | 1404-93-9 |
| Ifomula yeemolekyuli | I-C66H75Cl2N9O24.HCl |
| Ubunzima beMolekyuli | 1485.72 |
| Iinkcukacha zokuGcina | 2 ukuya ku-8 °C |
| IKhowudi yoMrhumo eHarmonized | 29419000 |
Ukucaciswa kweMveliso
| Amanzi | NMT 5.0% |
| Iintsimbi ezinzima | NMT 30ppm |
| pH | 2.5-4.5 |
| I-endotoxins yebhaktheriya | I-NMT 0.33EU/mg yeVancomycin |
| Ukucaca kwesisombululo | Cacileyo |
| Isivavanyi | 99% |
| Vancomycin B | NLT 900ug/mg |
| Umda we-monodechlorovancomycin | NMT 4.7% |
| Imbonakalo | Imhlophe, iphantse ibe mhlophe, okanye ibentsundu ukuya kumgubo opinki |
Iziganeko zosulelo lwe-methicillin-resistant Staphylococcus aureus olufunyenwe luluntu lukhula ngesantya esothusayo.Unyango olusebenzayo ngokwembali lubandakanya ukutshatyalaliswa kwangaphambili kunye nolawulo lwe-antibiotic.Olu phononongo lwenzelwe ukujonga ngokubonakalayo ukusebenza konyango lwe-empiric ekuphatheni izifo zesandla. Ulingo olulindelekileyo lwenziwa kwinqanaba lesibhedlele sesithili.Izigulana ezinosulelo lwesandla zifumene i-empiric intravenous vancomycin ekumkelweyo okanye nge-intravenous cefazolin.Iziphumo zalandelwa kusetyenziswa ubungqongqo bosulelo, impendulo efanelekileyo yeklinikhi, kunye nobude bokuhlala.Ukusebenza kweendleko kubalwa kusetyenziswa iindleko ezipheleleyo kwisigulane ngasinye kumaqela omabini.Uhlalutyo lwamanani lwenziwa.Izigulane ezingamashumi amane anesithandathu zabhaliswa kwisifundo.Amashumi amabini anesine ayenziwe ngokungaqhelekanga kwi-cefazolin (i-52.2 ekhulwini) kunye ne-22 (i-47.8 ekhulwini) kwi-vancomycin.Kwakungekho umehluko wezibalo phakathi kweendleko zonyango (p <0.20) okanye ubude bexesha lokuhlala (p <0.18) phakathi kwamaqela.Izigulane ezifakwe kwi-cefazolin zineendleko eziphezulu zonyango xa kuthelekiswa nezigulane ezifakwe kwi-vancomycin (p <0.05).Izigulane ezinosulelo olubi kakhulu zineendleko zeendleko zonyango (p <0.0001) kunye nexesha elide lokuhlala (p = 0.0002).Kufutshane nokuphela kophononongo, iziganeko ze-methicillin-resistant S. aureus kwisibhedlele sesithili sababhali zafunyaniswa ukuba zingama-72 ekhulwini, nto leyo eyabangela ukuba uphononongo lupheliswe kwangethuba yibhodi yophononongo yeziko ngenxa yeziganeko eziphezulu. Ukuthintela ukubanjwa kwe-randomization.Unyango olufanelekileyo lwakwangoko lwe-methicillin-resistant S. aureus alukaqinisekiswanga ngokuqinisekileyo.Akukho mahluko kwisiphumo sokusebenzisa i-cefazolin ngokuchasene ne-vancomycin njenge-arhente yomgca wokuqala ichongiwe.
