Iimveliso

Uphando lwePhytochemical lwesityalo sonke seLepisorus contortus (uKristu) iChing yakhokelela ekuhlukaniseni i-phenylethanoid glycosides entsha emihlanu (1-5), nganye iqulethe iqela le-caffeoyl, i-flavonoid glycoside entsha (10), kunye ne-14 eyaziwayo (6-9) kunye ne-11-15, i-syringic acid, i-vanillic acid, i-phloretic acid, i-diplopterol, kunye ne-β-sitosterol).Le yingxelo yokuqala ye-phenylethanoid glycosides evela kwintsapho yasePolypodiaceae.Ii-Compounds ze-1-15 zavandlakanywa ngenxa yekhono labo lomhlaza we-chemopreventive ngokusekelwe kumandla abo okuthintela i-tumor necrosis factor alpha (TNF-α)-eyenziwe ngumsebenzi we-NF-κB, ukuveliswa kwe-nitric oxide (NO), kunye ne-aromatase, i-quinone reductase 2 (QR-2) ), kunye ne-COX-1/-2 imisebenzi.I-Quercetin-3-O-β-d-glucoside (15) ibonise inhibition malunga ne-QR2 kunye ne-IC (50) ixabiso le-3.84 μM, eliqinisekisile i-kaempferol / quercetin glycosides njengezinto ezisebenzayo zokuvimbela i-QR2.I-compound iphinde ibonise umsebenzi we-NF-κB kunye nexabiso le-IC (50) le-33.6 μM.Ukongezelela, iikhompawundi 1, 2, 4, kunye ne-6 zibonise umsebenzi we-ar omatase kunye ne-IC (50) ixabiso le-30.7, 32.3, 26.8, kunye ne-35.3 μM, ngokulandelanayo.