Iimveliso

I-1-(2-Methoxyphenyl) i-piperazine hydrochloride, eyaziwa ngokuba yi-2-methoxyphenylpiperazine hydrochloride okanye i-2-MeOPP HCl, i-chemical compound kunye nezicelo ezahlukeneyo kwiinkalo ezahlukeneyo zesayensi, ngokukodwa kwi-chemistry yamayeza kunye nophando lwe-neuroscience.Enye yokusetyenziswa okukhulu kwe-1 -(2-Methoxyphenyl) i-piperazine hydrochloride kukusetyenziswa kwayo njenge-precursor kwi-synthesis ye-bioactive compounds.Le khompawundi isebenza njengebhloko yokwakha ukuveliswa kwamachiza axubileyo ajolise kwiindawo ezahlukeneyo zonyango, ezifana nokudakumba, ukuphazamiseka kokuxhalaba, kunye ne-schizophrenia.Ngokubandakanya i-2-methoxyphenylpiperazine moiety kwiimolekyuli zamachiza, abaphandi banokuguqula isakhiwo sokuphucula iimpawu ze-pharmacological kunye nokuphucula ukukhethwa kwe-receptors ethile kwinkqubo ye-nervous central. ii-receptors, kubandakanya i-serotonin kunye ne-dopamine receptors.Lo msebenzi uye wabangela ukuba kuphandwe ngesakhono sayo njengekhompawundi yengqondo kunye nesixhobo sokufunda ukuphazamiseka kwemithambo-luvo ezinxulumene nezi zamkeli.Ukuqonda ukusebenzisana kwale khompawundi kunye ne-receptors kwingqondo kunokubonelela ngengqiqo ebalulekileyo ekuphuhlisweni kweendlela zokungenelela zonyango.Ukongezelela, i-1-(2-Methoxyphenyl) i-piperazine hydrochloride ihlolwe indima yayo kwizifundo zemetabolism yamachiza.Isebenza njenge-metabolite yezinto ezithile ze-psychoactive, evumela abaphandi ukuba baqonde impendulo yomzimba kule mixube kunye neendlela ezichithwa ngayo.Le khompawundi inokunceda ekuchongeni nasekuqinisekiseni ubukho bamachiza angekho mthethweni okanye i-metabolites yabo kwiisampulu zebhayoloji, iyenza ibe sisixhobo esixabisekileyo kwi-forensic toxicology.Kubalulekile ukuqaphela ukuba i-1-(2-Methoxyphenyl) ipiperazine hydrochloride kufuneka iphathwe ngokufanelekileyo. inkathalo kunye nokubambelela kwizikhokelo zokhuseleko.Ulwazi olubanzi lwamaphepha edatha yokhuseleko kunye nokusetyenziswa kwezixhobo ezifanelekileyo zokukhusela zibalulekile ekuqinisekiseni ukuphathwa ngokukhuselekileyo kunye nokunciphisa iingozi ezinokubakho ezinxulumene nale khompawundi. .Ukusetyenziswa kwayo njengebhloko yokwakha kwi-synthesis yeziyobisi ivumela ukuphuhliswa kweekhompawundi kunye nezicelo zonyango ezinokubakho.Ukusebenzisana kwayo kunye ne-neurotransmitter receptors kwakhona kuyenza ibe sisixhobo esibalulekileyo sokuqonda ukuphazamiseka kwe-neurological kunye ne-metabolism yeziyobisi.Nangona kunjalo, amanyathelo okhuseleko afanelekileyo kufuneka athathwe ukuqinisekisa ukuphathwa ngokukhuselekileyo kunye nokunciphisa iingozi ezinokubakho xa kusetyenzwa nale khompawundi.