Iimveliso

I-1-(2,3-Xylyl) i-piperazine monohydrochloride, eyaziwa ngokuba yi-2,3-dimethoxyphenylpiperazine hydrochloride, i-chemical compound kunye nezicelo ezahlukeneyo kuphando lwamachiza kunye nophuhliso.Le ngqungquthela isetyenziswe ngokuyinhloko njengento ephakathi kwi-synthesis yee-molecules ezahlukeneyo ze-bioactive.Enye yezinto eziphambili zokusetyenziswa kwe-1-(2,3-Xylyl) i-piperazine monohydrochloride yindima yayo ekwakhiweni kweeamolekyu ezijolise kwinkqubo ye-nervous central.Ngokubandakanya i-2,3-dimethoxyphenylpiperazine moiety kwiimolekyuli zamachiza, abaphandi banokuguqula isakhiwo sabo sekhemikhali, ukuphucula iimpawu zabo ze-pharmacological kunye nokuphucula ubudlelwane babo kunye nokukhetha kwabo bamkeli abathile.Ngaphezu koko, i-1-(2,3-Xylyl) i-piperazine monohydrochloride ifunyenwe. ukuba nobudlelwane kwii-neuronal receptors ezahlukeneyo, kubandakanya i-serotonin kunye ne-dopamine receptors.Le propati ibangele umdla ekusetyenzisweni kwayo njengesixhobo sokufunda kunye nokuqonda ukuphazamiseka kwemithambo-luvo kunye neemeko zengqondo.Ngokuphanda ukusebenzisana kwale khompawundi kunye ne-receptors, abaphandi banokufumana ulwazi oluxabisekileyo kwiindlela eziphantsi kwezi meko, ezinokukunceda ekuphuhliseni ukungenelela kwezonyango zonyango.Uphando luye lwabonisa ukuba i-1-(2,3-Xylyl) i-piperazine monohydrochloride. ibonisa umsebenzi we-antimicrobial ngokuchasene neebhaktheriya ezithile kunye nomngundo.Esi sixhobo siye sakhokelela ekuhlolisweni kwayo njengesandulela esinokwenzeka ekuphuhliseni i-antimicrobial agents.Ngokuguqula isakhiwo sayo okanye ukuyifaka kwezinye iimolekyuli, abaphandi banokwenza iziyobisi ezinamandla kunye nezisebenzayo kunyango lwe-microbial infections.Kubalulekile ukuba uqaphele ukuba i-1-(2,3-Xylyl) piperazine monohydrochloride kufuneka iphathwe ngokuqaphela kwaye ngokubambelela kwiiprothokholi zokhuseleko ezifanelekileyo.Ulwazi lwamaphepha edatha yokhuseleko kunye nokusetyenziswa kwezixhobo ezifanelekileyo zokukhusela ziyimfuneko ekuqinisekiseni ukuphathwa ngokukhuselekileyo kunye nokunciphisa nayiphi na imingcipheko enokubakho ehambelana nale khompawundi.Ngesishwankathelo, i-1-(2,3-Xylyl) i-piperazine monohydrochloride iyikhompawundi eguquguqukayo enezicelo ezibalulekileyo uphando lwamayeza.Ukusetyenziswa kwayo njengento ephakathi kwi-synthesis yeziyobisi ivumela ukuphuhliswa kweeamolekyu kunye nezicelo zonyango ezinokubakho kwinkqubo ye-nervous central.Ukongezelela, ukuxhamla kwayo kwi-neuronal receptors kunye ne-antimicrobial properties kwenza ukuba ibe sisixhobo esixabisekileyo kwisifundo sokuphazamiseka kwengqondo kunye nezifo ezosulelayo.Nangona kunjalo, kufuneka kuthathelwe ingqalelo xa usebenza nale khompawundi ukuqinisekisa ukhuseleko kunye nokunciphisa iingozi ezinokubakho.