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I-1-(4-Fluorophenyl) piperazine dihydrochloride CAS: 64090-19-3

Inkcazelo emfutshane:

Inombolo Yekhathalogu: XD93330
Cas: 64090-19-3
Ifomula yeemolekyuli: I-C10H15Cl2FN2
Ubunzima beMolekyuli: 253.14
Ubukho: Ikhona evenkileni
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Inombolo Yekhathalogu XD93330
Igama lemveliso I-1-(4-Fluorophenyl) i-piperazine dihydrochloride
CAS 64090-19-3
Ifomu yemolekyulila I-C10H15Cl2FN2
Ubunzima beMolekyuli 253.14
Iinkcukacha zokuGcina I-Ambient

 

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I-1-(4-Fluorophenyl) i-piperazine dihydrochloride, eyaziwa ngokuba yi-4-FPP, i-chemical compound ifumana izicelo ezahlukeneyo kwiinkalo zamachiza kunye nophando.Isakhiwo sayo esikhethekileyo semolekyuli equlethe i-athomu ye-fluorine kunye ne-piperazine iringi yenza ukuba ixabiseke kwiinjongo ezahlukeneyo, ukusuka kuphuhliso lwamachiza ukuya kuphando lwezenzululwazi.Kushishino lwamachiza, i-1-(4-Fluorophenyl) i-piperazine dihydrochloride isebenza njengento ebalulekileyo ephakathi kwi-synthesis amayeza amaninzi onyango.Ngenxa yobuchule bayo bokwenza uhlengahlengiso lweekhemikhali, lenza ukuba kuyilwe abaviwa abatsha bamachiza abanomsebenzi wokwenza amayeza.Ubukho be-piperazine moiety kwisakhiwo sayo luncedo kakhulu ekuphuhliseni amayeza ajolise kwinkqubo ye-nervous central, njenge-antipsychotics, i-antidepressants, kunye ne-anti-anxiety agents.Ngaphezu koko, i-1-(4-Fluorophenyl) i-piperazine dihydrochloride isetyenziswa rhoqo uphando lwezenzululwazi ukuphanda iinkqubo ezahlukeneyo zebhayoloji.Njengesixhobo esisebenza ngeendlela ezininzi, isetyenziselwa ukufunda ukubopha i-receptor, ukusebenzisana kwe-neurochemical, kunye nemiphumo yamachiza kwiinkqubo ezithile emzimbeni.Abaphandi basebenzisa le khompawundi ukutyhila iindlela zesenzo samachiza ahlukeneyo, ukucacisa i-receptor subtypes, kunye nokuphonononga iindlela zokuhambisa umqondiso.Ngokufumana ukuqonda okunzulu kwezi nkqubo, izazinzulu zinokuqhubela phambili ulwazi olujikeleze ubuninzi beengxaki ze-neurological and psychiatric, zivula indlela yokuphuhliswa kweendlela zonyango zonyango.Ngaphezu koko, i-1-(4-Fluorophenyl) i-piperazine dihydrochloride isetyenziswa njenge-precursor ebalulekileyo I-synthesis ye-radioligands ye-positron emission tomography (PET).I-Radioligands esekelwe kule khompawundi, ebhalwe nge-isotopi ye-radioactive, ivumela ukubonwa okungathintekiyo kunye nobungakanani beenkqubo ezithile ze-biochemical emzimbeni womntu.Ubuchule bokucinga obunjalo bubonelela ngengqiqo ebalulekileyo ekuhanjisweni kwe-receptor, ukuhlala, kunye nokuxinana, ukuncedisa ekuhlolisweni kweemeko ezahlukeneyo ze-neurological kunye nokunceda ekuphuhliseni iindlela zonyango ezijoliswe kuzo.Kubalulekile ukuphatha i-1-(4-Fluorophenyl) i-piperazine dihydrochloride ngokuqaphela, njengoko ithathwa njengento enokuba yingozi.Amanyathelo afanelekileyo okhuseleko kunye nezixhobo zokukhusela zomntu kufuneka zisetyenziswe ukunciphisa umngcipheko wokuvezwa ngengozi okanye ukuphathwa kakubi.Isishwankathelo, i-1-(4-Fluorophenyl) ipiperazine dihydrochloride yikhompawundi eguquguqukayo esetyenziswa kumacandelo amayeza kunye nophando.Usetyenziso lwayo lubandakanya ukuhlanganiswa kweziyobisi, uphononongo lweenkqubo zebhayoloji, kunye nophuhliso lweeradioligands ze-PET imaging.Ulwazi lweempawu zekhompawundi kunye nokuphathwa ngononophelo kubalulekile ukuze kuqinisekiswe ukhuseleko kunye nokuququzelela igalelo layo elixabisekileyo kwinkqubela phambili yenzululwazi kunye neyeza.


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    I-1-(4-Fluorophenyl) piperazine dihydrochloride CAS: 64090-19-3