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iphepha_ibhena

Iimveliso

2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-enye Cas:1044871-04-6 Umfanekiso ofakiweyo
  • 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl) ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-enye Cas:1044871-04-6

2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl) ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-enye Cas:1044871-04-6

Inkcazelo emfutshane:

Inombolo Yekhathalogu: XD90961
Cas: 1044871-04-6
Ifomula yeemolekyuli: C24H29N3O4
Ubunzima beMolekyuli: 423.5
Ubukho: Ikhona evenkileni
Ixabiso:  
Ukupakisha kwangaphambili:  
Ipakethe enkulu: Cela iQuote

 


Iinkcukacha zeMveliso

Iithegi zeMveliso

Inombolo Yekhathalogu XD90961
Igama lemveliso 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-enye

CAS

 1044871-04-6

Ifomula yeemolekyuli

 C24H29N3O4

Ubunzima beMolekyuli

 423.5
Iinkcukacha zokuGcina  
IKhowudi yoMrhumo eHarmonized  

 

Ukucaciswa kweMveliso

Imbonakalo  
Isivavanyi  
Bindawo yokuthambisa 612.6±65.0 °C(Kuqikelelwe)
Ukuxinana 1.25±0.1 g/cm3(Kuxelwe kwangaphambili)
I-acidity coefficient (pKa)9.54±0.20(Iqikelelweyo)

 

I-RVX-297 inamandla kakhulu, i-BET inhibitor esebenzayo ngomlomo ekhethiweyo kwi-BD2.I-IC50s ye-RVX-297 ye-BRD2 (BD2), i-BRD3 (BD2), kunye ne-BRD4 (BD2) yayiyi-0.08, 0.05, kunye ne-0.02 μM, ngokulandelanayo.I-RVX-297 inqanda ukubonakaliswa kweentlobo ezahlukeneyo ze-immune cell inflammatory.Ukusebenza kwe-RVX-297 kwiimodeli zangaphambili zokuvuvukala okukrakra kunye nokuzimela.

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    2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl) ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-enye Cas:1044871-04-6

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