(2S, 3R) -2-Amino-3-hydroxybutanoic acid Cas: 72-19-5 99% I-crystalline powder emhlophe
| Inombolo Yekhathalogu | XD90285 |
| Igama lemveliso | (2S,3R) -2-Amino-3-hydroxybutanoic acid |
| CAS | 72-19-5 |
| Ifomula yeemolekyuli | C4H9NO3 |
| Ubunzima beMolekyuli | 119.11916 |
| Iinkcukacha zokuGcina | I-Ambient |
| IKhowudi yoMrhumo eHarmonized | 29225000 |
Ukucaciswa kweMveliso
| Isivavanyi | 99 - 101% |
| Imbonakalo | Umgubo omhlophe wekristale |
| Ukujikeleza okuthe ngqo | -27.5 ukuba -29.0 |
| Iintsimbi ezinzima | 10ppm max. |
| AS | 10ppm ubukhulu |
| pH | 5.2 - 6.5 |
| SO4 | <0.020% |
| Fe | 10ppm ubukhulu |
| Ilahleko ekomisweni | <0.20% |
| Intsalela kwi-Ignition | <0.10% |
| Ugqithiso | NLT 98% |
| Cl | <0.02% |
| Ityuwa ye-ammonium | <0.02% |
I-Serine / threonine protein phosphatases ichazwe kwiibhaktheriya ezininzi ze-pathogenic njengee-enzymes ezibalulekileyo ezibandakanyeka kwi-phosphorylation-ixhomekeke kwiindlela zokudlulisa umqondiso kwaye zihlala zihambelana nokuxhatshazwa kwezi zinto ziphilayo.Ukuhlolwa kwe-Mycoplasma synoviae genome kubonise ubukho bejini (prpC) efaka i-puative protein phosphatase ye-protein phosphatase 2C (PP2C) subfamily.Apha, sichaza i-biochemical characterization epheleleyo ye-M. synoviae phosphatase (PrpC) kunye nendima ethile ye-ion zetsimbi kwi-structure-function relationship yale enzyme.Uhlalutyo lokulandelelana kwe-amino acid ye-PrpC lubonise ukuba zonke iintsalela ezibandakanyekayo kwiziko lesinyithi se-dinuclear kunye neentsalela ze-ion-coordinating zentsimbi yesithathu, ezilondolozwe kwi-PP2C phosphatases, zikhona kwi-PrpC.I-PrpC yiprotheni ye-monomeric ekwazi ukukhupha i-phospho-substrates kunye nokuxhomekeka kwe-Mn (2+) ion '.Uhlalutyo lokuzinza kwe-Thermal lubonise ukuzinza kwe-enzyme kumaqondo obushushu aphakathi kunye nefuthe le-Mn (2+) ion kule propati.Uhlalutyo lwe-mass spectrometry lucebise ukuba ii-ion zetsimbi ezintathu zibophelela kwi-PrpC, ezimbini kuzo ezinobudlelwane obuphezulu obubonakalayo.Uhlalutyo lwenguquko lwentsalela yokulungelelaniswa kwentsimbi yesithathu, i-Asp122 kunye ne-Arg164, ibonise ukuba ezi zantlukwano zibonisa ukubophelela okubuthathaka kwee-ion zemanganese, kwaye zombini iinguqulelo zichaphazele umsebenzi we-PrpC phosphatase.Ngokwezi ziphumo, i-PrpC lilungu leprotein exhomekeke kwisinyithi kunye nozinzo oluphuculweyo kwifomu ye-holo kunye ne-Asp122, enokuthi ibandakanyeke kwindawo yesithathu yokubopha isinyithi, ibalulekile kumsebenzi wokuvuselela.
