Iimveliso

I-3-Quinolinecarboxylic acid, i-7-chloro-8-cyano-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, eyaziwa ngokuba yi-levofloxacin, yi-antibiotic ebanzi esetyenziswa ngokubanzi kunyango. yosulelo olwahlukeneyo lwebhaktiriya.Iphuma kwiklasi ye-fluoroquinolone ye-antibiotics kwaye ibonisa umsebenzi onamandla we-antimicrobial ngokuchasene ne-Gram-positive kunye ne-Gram-negative bacteria.I-Levofloxacin isetyenziswa ngokuqhelekileyo kulawulo lwezifo zokuphefumula ezifana ne-bronchitis kunye ne-pneumonia, kunye nosulelo lwe-urinary tract, isikhumba kunye usulelo lwezicubu ezithambileyo, kunye ne-bacterial prostatitis.Indlela yokusebenza kwayo ibandakanya ukuthintela i-bacterial DNA gyrase kunye ne-topoisomerase IV enzymes, eziyimfuneko ekuphindaphindeni kwe-DNA, ukulungiswa, kunye nokuphinda kuhlanganiswe kwiibhaktheriya.Ngokuphazamisa ezi enzymes, i-levofloxacin iphazamisa i-bacterial DNA synthesis, ekhokelela ekufeni kwe-bacterial cell.I-Levofloxacin ifakwe kakuhle ngomlomo kwaye ibonisa ukungena kwezicubu ezilungileyo, ivumela ukuba ifikelele ekugxininiseni okuphezulu kwindawo yokusuleleka.Le propati inegalelo ekusebenzeni kwayo ngokuchasene neentlobo ze-pathogens, kubandakanywa nezo zichasene nezinye ii-antibiotics.Ngaphaya koko, i-levofloxacin ibonisa isiqingatha sobomi obude, obuvumela ukuba kuthathwe idosi kube kanye ngemini, ukomeleza ukuthotyelwa kwesigulana kunye nokulula.Ukongeza kusetyenziso lwayo kunyango losulelo oluqhelekileyo lwebhaktheriya, i-levofloxacin ibonise umsebenzi ngokuchasene neentsholongwane ezingaqhelekanga ezifana neMycoplasma pneumoniae kunye neLegionella. pneumophila.Oku kwenza kube lukhetho olufanelekileyo lokunyanga iimeko zenyumoniya ezingaqhelekanga.Ngaphezu koko, i-levofloxacin ifunyenwe ukuba iphumelele ekupheliseni i-Helicobacter pylori, ibhaktheriya ehambelana nokuphuhliswa kwe-gastritis kunye nezilonda ze-peptic.Nangona kunjalo, kubalulekile ukuba uqaphele ukuba ukusetyenziswa kwe-levofloxacin kufuneka kwenziwe ngokuqaphela, ngokuqwalasela amandla iziphumo ezibi kunye nophuhliso lokumelana ne-antibiotic.I-Levofloxacin iye yadibaniswa nemiphumo emibi efana ne-nausea, isifo sohudo, intloko ebuhlungu, kunye nesiyezi.Akufanele isetyenziswe kubantu abane-hypersensitivity eyaziwayo kwi-fluoroquinolones okanye kwizigulana ezithile ezifana nabasetyhini abakhulelweyo, oomama abancancisayo, kunye nabantwana abangaphantsi kweminyaka eyi-18. -cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, okanye i-levofloxacin, i-antibiotic enamandla kwaye isetyenziswa ngokubanzi kunyango lwezifo zebhaktheriya.Umsebenzi wayo obanzi, ukungena kakuhle kwezicubu, kunye nerejimeni yedosi efanelekileyo kuyenza ibe lukhetho oluxabisekileyo lonyango.Nangona kunjalo, kufuneka kulumke xa kusetyenziswa, kuqwalaselwa iziphumo ebezingalindelekanga kunye nemfuneko yokulwa nokuxhathisa amayeza okubulala iintsholongwane.