Iimveliso

I-3,4,5-Trifluorophenylboronic acid yi-chemical compound enezicelo ezahlukahlukeneyo kwi-organic synthesis kunye nophando lwamachiza.Enye yezona zinto zisetyenziswayo ze-3,4,5-Trifluorophenylboronic acid njenge-boronic acid block block in transition metal-catalyzed cross. -iimpendulo zokudibanisa.Iyakwazi ukusabela ngee-electrophiles ezahlukeneyo, ezifana ne-aryl okanye i-vinyl halides, phantsi kweempembelelo ze-palladium catalyst, ukwenza i-carbon-carbon okanye i-carbon-heteroatom bonds.Oku kwenza ukuba kwakhiwe iimolekyuli ezintsonkothileyo, kubandakanywa amayeza, imichiza yezolimo, kunye nezinye iikhompawundi ezixabisekileyo.I-trifluorophenyl substituent kwi-compound iphucula ukusebenza kwayo kwaye inokuchaphazela ukukhethwa kwendlela yokusabela, iyenze ibe sisixhobo esiluncedo kwi-organic synthesis.Kwikhemikhali yamayeza, i-3,4,5-Trifluorophenylboronic acid kunye ne-derivatives yayo inomdla ngokukodwa njengabaviwa beziyobisi. .Iqela le-trifluorophenyl liyakwazi ukulungelelanisa intsebenziswano yekhompawundi kunye neethagethi zebhayoloji, ezifana ne-enzymes okanye i-receptors, ekhokelela ekuguqulweni kweepropati ze-pharmacological.Inokuphucula amandla, ukukhetha, okanye ukuzinza kwe-metabolic yekhompawundi, iyenze ibe yibhloko ekhangayo yokwakha kuphuhliso lwamachiza.Ukongezelela, i-boronic acid moiety ekhoyo kwi-3,4,5-Trifluorophenylboronic acid inokwenza i-reversible covalent bonds kunye ne-enzyme ethile, inikezela ngamathuba oyilo lwe-enzyme inhibitors.Ngaphezu koko, i-3,4,5-Trifluorophenylboronic acid inokufumana izicelo kwisayensi yezinto. .Ingasetyenziswa ekudibaneni kwezinto eziphambili, kubandakanywa iipolymers okanye i-metal-organic frameworks, ukwazisa iipropati ezinqwenelekayo.Ubukho beqela le-trifluorophenyl bunokuchaphazela ukunyibilika kwezinto, ukuzinza kwe-thermal, okanye iipropati ze-elektroniki, okwenza ukuba zilungele ukusetyenziswa kwezinto ezahlukeneyo, ezifana ne-sensing, i-catalysis, okanye izixhobo ze-optoelectronic. Ihlanganiswe nesixhobo esibalulekileyo kwi-organic synthesis, chemistry yamayeza, kunye nesayensi yezixhobo.Ukubandakanyeka kwayo kwinguqu ye-metal-catalyzed cross-coupling reactions ivumela ukwakhiwa kwee-molecule eziyinkimbinkimbi, kunye ne-trifluorophenyl substituent yayo iphakamisa ukusebenza kwayo kunye nokukhetha.Kwimichiza yamayeza, ingasetyenziselwa ukuphuhlisa abaviwa abanokuba ngamachiza ngokumodareyitha intsebenziswano kunye neethagethi zebhayoloji.Ukongeza, ukufakwa kwayo kwizinto eziphambili kwenza ukuyilwa kwezinto ezineempawu ezilungiselelwe.