Cytidine-5'-triphosphate disodium ityuwa CAS:36051-68-0 95%
| Inombolo Yekhathalogu | XD90568 |
| Igama lemveliso | Cytidine-5'-triphosphate disodium ityuwa |
| CAS | 36051-68-0 |
| Ifomula yeemolekyuli | I-C9H14N3Na2O14P3 |
| Ubunzima beMolekyuli | 527.120 |
| Iinkcukacha zokuGcina | 2 ukuya ku-8 °C |
| IKhowudi yoMrhumo eHarmonized | 29349990 |
Ukucaciswa kweMveliso
| Imbonakalo | Umgubo omhlophe |
| Isivavanyi | 99% |
Ukunyangwa kweeseli ezincancisayo ngamachiza e-chemotherapeutic kunokubangela ukuphazamiseka kwamachibi e-nucleotide.Ukubeka esweni ezi perturbations kwiiseli ithumba cultured ukusuka kwimithombo yabantu luncedo kuvavanyo isiphumo unyango ngamachiza kunye nokuqonda ngcono indlela yokusebenza kwala machiza.Kolu phononongo, iiklasi ezintathu zamachiza e-chemotherapeutic aneendlela ezahlukeneyo zokusebenza zasetyenziswa ekuphuhliseni iimodeli zeeseli eziphathwe ngamachiza.Uhlalutyo olujoliswe kwi-LC olujoliswe kwi-metabolomics ye-nucleotides kwiiseli zeqela lokulawula kunye neqela eliphathwe ngamachiza lenziwa.Iindlela ezininzi zokusetyenzwa kwedatha zadityaniswa ukuchongwa kweempawu zebhayoloji ezinokubakho ezinxulumene nesenzo samachiza, kubandakanywa uhlalutyo lwendlela enye yokwahluka, ukuhlalutya kwecandelo eliphambili, kunye neejika zeempawu zokusebenza kommkeli.Ngokuthakazelisayo, iiseli ze-tumor zombini iqela lokulawula kunye namaqela aphathwe ngamachiza ayakwazi ukwahlula omnye komnye, kwaye iinguqu ezininzi zaqatshelwa njenge-potentia l biomarkers, njenge-ATP, GMP, kunye ne-UDP ye-antimetabolite agents, i-ATP, i-GMP, kunye ne-CTP. kwi-agent ezonakalisa i-DNA, kunye ne-GMP, i-ATP, i-UDP, kunye ne-GDP ye-mitotic spindle agents.Uqinisekiso olongezelelweyo lweempawu zebhayoloji ezinokubakho zenziwa kusetyenziswa ijiko leempawu zokusebenza komamkeli.Ukuqwalasela indawo yabo ehambelanayo phantsi kwejika, eyayinkulu kune-0.9, kunokugqitywa ukuba i-GMP kunye ne-ATP zezona zibalaseleyo ze-biomarkers ze-DNA-zonakalisa iziyobisi, kunye ne-GMP, i-ATP, kunye ne-UDP kwezinye iindidi ezimbini zamachiza.Le ndlela yokunciphisa i-nucleotide ayikwazi ukuhlula ngokupheleleyo iindlela zamachiza alithoba, kodwa inika ubungqina bokuqala bendima ye-pharmacotabolomics ekuphuhlisweni kwangaphambili kwamachiza ubuncinane.
