![4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-N-Methylsulfonyl)Amino]Pyrimidinyl-5-Yl-Formyl CAS: 147118-37-4 Umfanekiso ofakiweyo](http://cdn.globalso.com/xdbiochems/白色粉末1046.jpg)
![4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-N-Methylsulfonyl)Amino]Pyrimidinyl-5-Yl-Formyl CAS: 147118-37-4](http://cdn.globalso.com/xdbiochems/粉末148.jpg)
4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-N-Methylsulfonyl)Amino]Pyrimidinyl-5-Yl-Formyl CAS: 147118-37-4
| Inombolo Yekhathalogu | XD93414 |
| Igama lemveliso | 4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-N-Methylsulfonyl)Amino]Pyrimidinyl-5-Yl-Formyl |
| CAS | 147118-37-4 |
| Ifomu yemolekyulila | I-C16H18FN3O3S |
| Ubunzima beMolekyuli | 351.4 |
| Iinkcukacha zokuGcina | I-Ambient |
Ukucaciswa kweMveliso
| Imbonakalo | Umgubo omhlophe |
| uAsay | 99% imizuzu |
I-4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-N-Methylsulfonyl)Amino]I-Pyrimidinyl-5-Yl-Formyl, eyaziwa ngokuba yi-FIMPA, i-chemical compound kunye nesakhiwo esiyinkimbinkimbi esinamandla. izicelo kuphando lwamachiza kunye nophuhliso lwamachiza.Ihlelwa njenge-derivative ye-pyrimidine kunye neqela le-formyl elifakwe kwi-athomu ye-5 ye-carbon, kunye ne-4-fluorophenyl kunye neqela le-isopropyl eliqhotyoshelwe kwi-4th kunye ne-6 ye-athomu ye-carbon, ngokulandelanayo.Enye yezicelo ezibalulekileyo ze-FIMPA zisendle uphando lomhlaza.I-Pyrimidine derivatives ifundwe ngokubanzi kwiipropati zabo ze-antitumor, kwaye i-FIMPA ibonisa amandla njenge-agent ye-anticancer.Iimpawu zayo zesakhiwo zenza ukuba ngumviwa othembisayo wokuthintela i-enzymes eziphambili okanye ii-receptors ezibandakanyekayo ekukhuleni kwe-tumor kunye nokuqhubela phambili.Abaphandi banokuguqula isakhiwo se-FIMPA ngakumbi ukunyusa amandla ayo, ukukhetha, kunye neempawu ze-pharmacokinetic zonyango olusebenzayo lomhlaza.Ngaphezu koko, i-FIMPA inokusebenza njenge-scaffold ye-molecular yokuphuhlisa abaviwa beziyobisi ezijolise kwezinye izifo.Isakhiwo salo esiyingqayizivele sivumela ukudibanisa kwamaqela ahlukeneyo asebenzayo, anokuthi adlale indima ebalulekileyo ekusebenzisaneni neethagethi ezithile ze-molecular.Oku kuguquguquka kwenza i-FIMPA ibe sisixhobo esibalulekileyo kwi-chemistry yonyango ekuphuhliseni ii-agent zonyango ezinoveli ezichasene nezifo ezahlukahlukeneyo ezifana nokuphazamiseka kwe-neurological okanye izifo ezosulelayo.Amaqela ayo asebenzayo asebenzayo, afana namaqela e-formyl kunye ne-sulfonyl, anokusebenza njengeziza zohlengahlengiso olongezelelweyo lwemichiza.Abaphandi banokusebenzisa i-FIMPA njengento yokuqala okanye i-compound ephakathi ukufikelela kwi-derivatives eyahlukeneyo, enokuthi ihlolwe kwimisebenzi yabo ye-biological okanye isetyenziswe njengeebhloko zokwakha ukuhlanganiswa kwee-molecule eziyinkimbinkimbi. Ngokubanzi, i-4- (4-Fluorophenyl) -6-Isopropyl -2 - [(N-Methyl-N-Methylsulfonyl)Amino]Pyrimidinyl-5-Yl-Formyl (FIMPA) ibonisa amandla athembisayo kwiindawo ezahlukeneyo zophando lwamachiza kunye nophuhliso lweziyobisi.Ubume bayo obukhethekileyo kunye namaqela asebenzayo ayenza ibe sisixhobo esibalulekileyo sokuyila abaviwa abatsha beziyobisi okanye ukudibanisa iikhompawundi eziyinkimbinkimbi ze-organic.Ukuphononongwa ngakumbi kunye nokuphucula iipropathi zeFIMPA kunokukhokelela ekufunyanweni kweearhente zonyango ezinoveli kwaye kube negalelo kwinkqubela phambili kwicandelo lekhemistri yamayeza.
