Iimveliso

I-4-Phenoxyphenylboronic acid yikhemikhali yekhemikhali enokusetyenziswa ngeendlela ezahlukeneyo kwiinkalo ezahlukeneyo, kubandakanywa amayeza, uphando, kunye ne-organic synthesis.Le khompawundi, kunye nokusebenza kwayo kwe-boronic acid, inika iipropati ezininzi ezikhethekileyo ezenza ibhloko yokwakha exabisekileyo ekuphuhliseni iamolekyu ezintsha kunye nezinto eziphathekayo.Enye isicelo esibalulekileyo se-4-Phenoxyphenylboronic acid kuphando lwamachiza kunye nophuhliso.I-Boronic acids ifumene ingqwalasela kwishishini lamachiza ngenxa yokukwazi kwabo ukwenza i-covalent bond reversible covalent kunye ne-biomolecules ezithile, ezifana neeprotheni kunye ne-enzymes.Le propati ivumela ukuyilwa kweziyobisi ezisekelwe kwi-boronic acid ezinokujolisa ngokukhethiweyo kwiithagethi ezithile zebhayoloji, ezifana ne-enzymes ezibandakanyekayo kwizifo ezifana nomhlaza okanye isifo seswekile.Abaphandi banokusebenzisa i-4-Phenoxyphenylboronic acid njengento yokuqala ukudibanisa abaviwa beziyobisi ze-boronic acid kunye nokuphonononga izicelo zabo zonyango ezinokubakho.Ukongezelela kwi-pharmaceuticals, i-4-Phenoxyphenylboronic acid iphinda ifumane ukusetyenziswa kwi-organic synthesis.Iqela le-asidi ye-boronic kule khompawundi inokuchaphazeleka ngeendlela ezahlukeneyo, kubandakanya iSuzuki-Miyaura yokuhlangana kwe-cross-coupling reactions.Ezi mpendulo ziquka ukudibanisa i-asidi ye-boronic kunye neentlobo ezahlukeneyo ze-organic halides okanye i-triflates, ekhokelela ekubunjweni kweebhondi ze-carbon-carbon.Oku kuguquguquka kuvumela iikhemisti ukuba zenze iimolekyuli zendalo ezintsonkothileyo, ezinjengeemveliso zendalo, iikhemikhali ze-agrochemicals, kunye nezixhobo eziphambili.I-4-Phenoxyphenylboronic acid isebenza njenge-precursor exabisekileyo kule migudu yokwenziwa.Ngaphezu koko, i-4-Phenoxyphenylboronic acid iphinda isetyenziswe kwizicelo zophando, ngokukodwa kwintsimi ye-chemical biology kunye ne-bioconjugation.I-Boronic acids isetyenziswe ekuphuhliseni i-fluorescent probes, i-sensors, kunye ne-imaging agents zokubona kunye nokubona i-biomolecules ethile okanye iziganeko zeselula.Ngokubandakanya i-4-Phenoxyphenylboronic acid ekuyilweni kwezi probes, abaphandi banokwenza izixhobo ezikhethiweyo kunye nezibucayi zokufunda iinkqubo ze-biological in vitro kunye ne-vivo. kunye nebhayoloji yemichiza.Ukusebenza kwayo kwe-boronic acid ivumela ukuyilwa kunye nokuhlanganiswa kwabaviwa bamachiza anoveli kunye neenzuzo zonyango ezinokubakho.Isebenza njengebhloko yokwakha eluncedo ekudalweni kwee-molecule ze-organic complex.Ukongeza, kwizicwangciso zophando, igalelo kuphuhliso lwezixhobo zokufunda iinkqubo zebhayoloji.Ngokubanzi, i-4-Phenoxyphenylboronic acid yinto exabisekileyo, eyenza ukuqhubela phambili kwiinkalo ezahlukeneyo zesayensi.