Iimveliso

I-Agmatine yimveliso ye-decarboxylation ye-arginine catalyzed yi-L-arginine decarboxylase (L-ADC).Yi-neurotransmitter kwaye isasazwa kumalungu amaninzi kunye nezicubu kwizilwanyana ezanyisayo.I-organ-specific, efana neeseli ze-adrenal chromaffin, iiseli zeglial, kunye ne-carotid body spherocytes.Idatha yophando ibonisa ukuba i-agmatine inemisebenzi yezinto eziphilayo ezifana nokunciphisa iswekile yegazi, ukunciphisa uxinzelelo lwegazi, i-diuresis, i-anti-inflammatory, i-antidepressant, kunye ne-inhibiting cell proliferation, ingakumbi umphumo wayo ochasayo kwi-N-methyl-D-aspartate receptors.Inamandla kwaye ihlala njalo, kwaye inefuthe lokurhoxiswa kweekhemikhali kwi-morphine yezilwanyana.Luhlobo lokukhutshwa kweziyobisi kunye nexabiso elikhulu lophuhliso.Njengetyuwa yezamayeza ye-agmatine, i-agmatine sulfate inombono obanzi wesicelo semarike.Kwaye i-agmatine isebenza ngokukhuthaza ukukhululwa kwamahomoni kwi-hypothalamus, kuquka i-hormone ye-luteinizing kunye ne-hormone yokukhula, kwaye inyusa amanqanaba e-nitric oxide ngeendlela ezimbini: ukukhuthaza ukukhutshwa kwe-nitric oxide kunye nokuvimbela ukuhlanganiswa kwe-nitric oxide, enokunyusa amanqanaba e-nitric oxide.Ukuphucula ukunyamezela komzimba, ukukhawuleza ukubuyiswa komzimba (ngokubanzi emva kokuzivocavoca umzimba), kuphucula ukusebenza komzimba, kubonisa ukuthuthwa kwamandla okumangalisayo kunye nexesha elide, kunye nokuphucula ukubunjwa komzimba wonke.

I-Agmatine inemisebenzi yebhayoloji efana nokwehlisa iswekile yegazi, ukuthoba uxinzelelo lwegazi, i-diuresis, i-anti-inflammatory, antidepressant, kunye nokuthintela ukwanda kweeseli.Unempembelelo yokurhoxisa kwizilwanyana ezixhomekeke kwi-morphine kwaye luhlobo lokukhutshwa kweziyobisi kunye nexabiso elikhulu lophuhliso.