I-Amphotericin B CAS: 1397-89-3 umgubo omthubi okanye oOrenji
| Inombolo Yekhathalogu | XD90365 |
| Igama lemveliso | Amphotericin B |
| CAS | 1397-89-3 |
| Ifomula yeemolekyuli | C47H73NO17 |
| Ubunzima beMolekyuli | 924.08 |
| Iinkcukacha zokuGcina | 2 ukuya ku-8 °C |
| IKhowudi yoMrhumo eHarmonized | 29415000 |
Ukucaciswa kweMveliso
| Salmonella | Ibi |
| I-acetone | 5000ppm max |
| Ilahleko ekomisweni | 5.0% ubukhulu |
| Inkcazo | USP 38 |
| I-Ethanol | 5000ppm max |
| Intsalela kwi-Ignition | <3% |
| Imbonakalo | Umgubo otyheli okanye oOrenji |
| Ubalo lweAerobic iyonke | ≤ 100CFU/g |
| Escherichia coli | Ibi |
| Isivavanyi | ≥ 750μg/mg |
Ijeli ye-Chitosan-dextran isetyenziswe njenge-antihemostatic agent kunye ne-antiadhesive agent emva kokuhlinzwa kwe-sinus endoscopic.Ngenxa yokuba i-Staphylococcus aureus biofilms iye yabandakanyeka kwi-recalcitrant chronic rhinosinusitis, olu phononongo lujolise ekuphandeni ngakumbi (i) ukuchasana nokudumba, (ii) inhibition yebhaktiriya ye-biofilm, (iii) imiphumo echasayo, kunye (iv) neempawu zokupholisa amanxeba e-chitosan kunye I-chitosan-dextran gel.I-Fibroblasts yahlukaniswa nezicubu zempumlo yomntu kwaye yayisetyenziselwa ukumisela imiphumo ye-chitosan kunye ne-chitosan-dextran gel kwi-(i) ukwanda kweeseli, (ii) ukuphulukiswa kwesilonda, (iii) ukuvuvukala kwiinkcubeko ze-fibroblast ezinomngeni kunye ne-superantigens S. I-aureus enterotoxin B (SEB) kunye ne-toxic shock syndrome toxin (TSST), kunye (iv) kwi-S. aureus biofilms.I-Chitosan yayisebenza kakhulu ekunciphiseni ukubonakaliswa kwe-IL-8 emva komngeni we-TSST kunye ne-SEB.I-Chitosan iphinde yasebenza ekwehliseni i-IL-8 ukubonakaliswa kwe-fibroblasts engacetywanga ebonisa iziphumo zayo zokuchasa ukudumba kwi-fibroblasts kwimeko yentengiso.I-gel ye-Chitosan-dextran ibonise iimpawu ezinamandla ze-antibiofilm kwi-50% (v / v) yoxinaniso kwi-vitro.I-Dextran, ngokwayo, ibonise iimpawu ze-antibiofilm kwi-concentration ye-1.25% (w / v).I-Chitosan, ngokwayo, yanciphisa ukwanda kwe-fibroblasts ukuya kwi-82% yokulawula ukwanda kunye ne-chitosan-dextran gel yanciphisa ukwanda kwe-fibroblasts kwi-0.04% yokulawula ukwanda.Ngokumalunga nokulawulwa konyango, i-gel ye-chitosan-dextran ilibazise kakhulu izinga lokupholisa isilonda kwiiyure zokuqala ze-48 zovavanyo. ixesha.I-Chitosan yanciphisa amanqanaba e-IL-8, ebonisa iimpawu zayo ezichasayo.Ijeli ye-Chitosan-dextran kunye nonyango lwe-dextran lubonise iimpawu ze-antibiofilm kwimodeli yethu.
