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Iimveliso

BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine ityuwa Cas:6578-06-9 99% Imhlophe ukuya kumgubo okhanyayo omdaka obonakalayo
  • BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine ityuwa Cas:6578-06-9 99% Imhlophe ukuya kumgubo omdaka okhanyayo

BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine ityuwa Cas:6578-06-9 99% Imhlophe ukuya kumgubo omdaka okhanyayo

Inkcazelo emfutshane:

Inombolo Yekhathalogu: XD90137
Cas: 6578-06-9
Ifomula yeemolekyuli: C8H5BrClNO4P·C7H10N
Ubunzima beMolekyuli: 433.62
Ubukho: Ikhona evenkileni
Ixabiso:  
Ukupakisha kwangaphambili: 5g USD20
Ipakethe enkulu: Cela iQuote

 

 

 

 

 

 

 


Iinkcukacha zeMveliso

Iithegi zeMveliso

Inombolo Yekhathalogu XD90137
Igama lemveliso I-BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine ityuwa
CAS 6578-06-9
Ifomula yeemolekyuli C8H5BrClNO4P·C7H10N
Ubunzima beMolekyuli 433.62
Iinkcukacha zokuGcina -15 ukuya -20 °C
IKhowudi yoMrhumo eHarmonized 29339980

 

Ukucaciswa kweMveliso

Imbonakalo Umgubo omhlophe/okhanyayo omdaka
uAsay ≥ 99%
Indawo yokunyibilika 194-195 ºC
Indawo yokubilisa 580.2 ° C kwi-760 mmHg
Indawo yokuflasha 304.7°C
Ukunyibilika I-DMF: 20 mg/mL
Ukunyibilika Inyibilika kwi-dimethylformamide, ayinyibiliki emanzini.
Uvakalelo Iyavelana nokukhanya, iyavela emoyeni, kwaye inochuku kubushushu

 

Umsebenzi webhayoloji: I-BCIP (i-BCIP p-toluidine ityuwa; ityuwa ye-X-phosphate p-toluidine) yi-chromogenic substrate yokubhaqa i-colorimetric yomsebenzi we-alkaline phosphatase.

I-Shiga toxins (Stxs) iveliswa yi-enterohemorrhagic Escherichia coli (EHEC), ebangela ukusuleleka kwabantu kunye nesiphumo esihlala sibulala.Imigca yeseli yeVero, ephuma kwintso yenkawu eluhlaza yaseAfrika, imele umgangatho wegolide wokumisela iziphumo ze-cytotoxic ze-Stxs.Nangona ukusetyenziswa kwabo kwehlabathi jikelele, ulwazi malunga nezakhiwo ezichanekileyo ze-Stx receptor glycosphingolipids (GSLs) kunye nendibano yabo kwi-lipid rafts ihlwempu.Apha sibonisa uhlalutyo olubanzi lwesakhiwo se-Stx receptor GSL kunye nokusabalalisa kwi-detergent-resistant membranes (DRMs), ezilungiselelwe ukusuka kwiiseli ze-Vero-B4 kwaye zisetyenziswe njenge-lipid raft equivalents.Siye sachonga i-globotriaosylceramide (Gb3Cer) kunye ne-globotetraosylceramide (Gb4Cer) njenge-GSL receptors ye-Stx1a, i-Stx2a, kunye ne-Stx2e subtypes zisebenzisa ukufunyanwa kwe-TLC yokwaleka ngokudibeneyo kunye ne-MS.I-Stx receptor engaqhelekanga, i-globopentaosylceramide (Gb5Cer, Galβ3GalNAcβ3Galα4Galβ4Glcβ1Cer), eyayiqatshelwe ngokukodwa (ngaphezu kwe-Gb3Cer kunye ne-Gb4Cer) ngu-Stx2e, ibonakaliswe ngokupheleleyo.I-Lipoforms ye-Stx receptor GSLs yafunyanwa ikakhulu kwi-harbor ceramide moieties eyenziwe nge-sphingosine (d18: 1) kunye ne-C24: 0 / C24: 1 okanye i-C16: i-0 fatty acid.Ngaphaya koko, ukwenzeka ngokubambisana kunye ne-lipid raft markers, i-SM kunye ne-cholesterol, kwii-DRM zicebise unxulumano lwe-GSL kunye ne-membrane microdomains.Olu pho nonongo lubonelela ngesiseko sokuphonononga ngakumbi impembelelo esebenzayo ye-lipid raft-ehambelana ne-Stx receptors yokulimala kwe-toxin yeeseli ze-Vero-B4.

 

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    BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine ityuwa Cas:6578-06-9 99% Imhlophe ukuya kumgubo omdaka okhanyayo

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