Iimveliso

Carbamic acid, [(1R) -3-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl] -3-oxo -1 - [(2,4,5-trifluorophenyl) methyl]propyl]-, 1,1-dimethylethyl ester, eyaziwa ngokuba negama layo elicwangcisiweyo, i-compound yekhemikhali eyinkimbinkimbi enezicelo ezinokubakho kwiinkalo ezahlukeneyo, kubandakanywa amayeza kunye ne-agrochemicals. .Kwishishini lamachiza, iCarbamic acid, [(1R) -3-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)- yl] -3-oxo-1-[(2,4,5-trifluorophenyl) methyl]propyl]-, i-1,1-dimethylethyl ester ingasetyenziswa njengendawo ephakathi kwi-synthesis yamachiza.Ulwakhiwo lwayo oluguquguqukayo luvumela ukuguqulwa kunye nokusebenza, okwenza ukuba ukudalwa kwabaviwa bamachiza anoveli.Ubukho beqela le-trifluoromethyl kwandisa i-lipophilicity yekhompawundi, enokuthi iphucule ukufumaneka kwayo kwezinto eziphilayo kunye nokwandisa ukusebenza kwayo kunyango.Ukongezelela, i-triazolopyrazine moiety iyaziwa ukuba inomsebenzi we-biological, okwenza ibe yi-scaffold ekhangayo yokuphuhliswa kweziyobisi.Ngaphezu koko, i-Carbamic acid, [(1R) -3--[5,6-dihydro-3-(trifluoromethyl)) -1,2, I-4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl]-, i-1,1-dimethylethyl ester ingafumana izicelo kwi-agrochemicals.Ulwakhiwo olulodwa lwale khompawundi kunye namaqela asebenzayo luyenza ibe ngumntu onokubakho kuphuhliso lwezitshabalalisi okanye imichiza yokutshabalalisa ukhula.I-trifluoromethyl kunye namaqela e-trifluorophenyl anokuphucula umsebenzi we-compound kunye nokuzinza, ukuvumela ukulawulwa okujoliswe kuyo kunye nokusebenza kakuhle kwezinambuzane kunye nokhula kwezolimo.Ngaphezu koko, ukusetyenziswa okunokwenzeka kweCarbamic acid, [(1R) -3-[5,6-dihydro-3] -(trifluoromethyl) -1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl]- , I-1,1-dimethylethyl ester yandisa ngaphaya kwee-pharmaceuticals kunye ne-agrochemicals.Ulwakhiwo lwalo olulodwa lunokulungela usetyenziso kwinzululwazi yemathiriyeli, njengophuhliso lweepolima ezisebenzayo, iikristale zolwelo, okanye idayi.Ukuguqulwa kwesakhiwo se-compounds kunokukhokelela kwizinto eziphathekayo ezihambelanayo, kuquka i-optical, i-electronic, okanye i-mechanical features.Ukugqiba, i-Carbamic acid, [(1R) -3- [5,6-dihydro-3- (trifluoromethyl) -1], 2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl]-, 1,1-dimethylethyl ester yikhompawundi entsonkothileyo enezicelo ezinokubakho kumayeza, kumachiza ezolimo, nakwinzululwazi yemathiriyeli.Ubume bayo obubodwa kunye namaqela asebenzayo abonelela ngamathuba okuphuhliswa kwabaviwa bamachiza anoveli, izitshabalalisi, kunye nezixhobo zokusebenza.Nangona kunjalo, uphando olongezelelweyo kunye nokuhlola kuyimfuneko ukuqonda ngokupheleleyo amandla alo kunye nokwandisa ukusetyenziswa kwayo kumashishini ahlukeneyo.